SCHEMBL20577112

SCHEMBL20577112

O=C(OC(=O)c1cc(Cl)c(Cl)c(Cl)c1Cl)c1cc(Cl)c(Cl)c(Cl)c1Cl

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.43
TSHR P16473 6/20 0.41
HPGD P15428 5/20 0.41
HSD17B10 Q99714 5/20 0.41
HSP90AA1 P07900 1/20 0.41
MAPK1 P28482 1/20 0.36
AKR1B1 P15121 1/20 0.35
GAA P10253 1/20 0.34
CASP1 P29466 2/20 0.33
CRHBP P24387 1/20 0.33
CRHR2 Q13324 1/20 0.33
KMT2A Q03164 2/20 0.31
MAPT P10636 1/20 0.31
ALDH1A1 P00352 3/20 0.31
TP53 P04637 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
AHR P35869 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11406014 0.86 CYP3A4 (0.43) CYP3A4TSHRHPGDHSD17B10HSP90AA1
SCHEMBL5493096 0.86 F2 (0.42) TSHRHPGDHSD17B10MAPK1GAA
SCHEMBL8331805 0.83 GAA (0.51) CYP3A4HPGDGAAKMT2ASMN1; SMN2
SCHEMBL9328634 0.78 CA12 (0.46) CYP3A4HPGDHSD17B10KMT2AMAPT
SCHEMBL9328809 0.78 CYP4F2 (0.51) TSHRHSD17B10MAPK1GAACASP1
SCHEMBL194772 0.78 CYP3A4 (0.36) CYP3A4TSHRHPGDHSD17B10HSP90AA1
SCHEMBL9327893 0.78 CA12 (0.38) CYP3A4TSHRHPGDHSD17B10HSP90AA1
SCHEMBL20513001 0.77 CYP3A4 (0.41) CYP3A4TSHRMAPK1CASP1KMT2A
SCHEMBL1315659 0.76 CYP3A4 (0.48) CYP3A4TSHRHPGDHSD17B10HSP90AA1
SCHEMBL1437003 0.76 CYP3A4 (0.48) CYP3A4TSHRHPGDHSD17B10HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118005003-B Ultra-micro porous hard carbon material and preparation method and application thereof 成都锂能科技有限公司 2024-06-18 CN disclosed
CN-118005003-A Ultra-micro porous hard carbon material and preparation method and application thereof 成都锂能科技有限公司 2024-05-10 CN disclosed
CN-115627559-B Degradable filament and special material thereof 北京微构工场生物技术有限公司 2023-05-16 CN disclosed
EP-4098683-A1 METHOD FOR PRODUCING RECYCLED THERMOPLASTIC RUBBER MASTERBATCH WITH IMPROVED GREEN STRENGTH AND TACK Tyrec Ltd. (IL) 2022-12-07 EP disclosed
CN-114196227-A Process for the preparation of isoindolinone pigments 百合花集团股份有限公司 2022-03-18 CN disclosed
US-11034822-B2 Method for producing recycled thermoplastic rubber masterbatch with improved green strength and tack Tyrec Ltd. (IL) 2021-06-15 US disclosed
US-20200181372-A1 METHOD FOR PRODUCING RECYCLED THERMOPLASTIC RUBBER MASTERBATCH WITH IMPROVED GREEN STRENGTH AND TACK Tyrec Ltd. (IL) 2020-06-11 US disclosed
EP-3630876-A1 METHOD FOR PRODUCING RECYCLED THERMOPLASTIC RUBBER MASTERBATCH WITH IMPROVED GREEN STRENGTH AND TACK Tyrec Ltd. (IL) 2020-04-08 EP disclosed
WO-2018220618-A1 METHOD FOR PRODUCING RECYCLED THERMOPLASTIC RUBBER MASTERBATCH WITH IMPROVED GREEN STRENGTH AND TACK Tyrec Ltd. (IL) 2018-12-06 WO disclosed
CN-1222519-A Preparation of tetrachlorobenzene anhydride ZHANG WEN (CN) 1999-07-14 CN disclosed