Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.51 |
| ▸ | SHBG | P04278 | 2/20 | 0.51 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | AR | P10275 | 5/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2318050 | 1.00 | CYP19A1 (0.51) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL1421923 | 1.00 | CYP19A1 (0.51) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL16661465 | 1.00 | CYP19A1 (0.51) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL3643471 | 0.83 | CYP19A1 (0.62) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL13372732 | 0.83 | CYP19A1 (0.62) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL11148382 | 0.83 | SLC6A4 (0.50) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL2317206 | 0.83 | PGR (0.47) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL2341440 | 0.83 | PGR (0.47) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL10533302 | 0.81 | PGR (0.45) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL11140879 | 0.81 | PGR (0.52) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354945-B1 | PROCESS FOR THE ENHANCEMENT OF ENZYME ACTIVITIES AND SYNTHETIC EFFICIENCY IN MICROORGANISMS AND HIGHER PLANTS | SCHERING AG (DE) | 1994-03-23 | — | — | EP | disclosed |
| EP-0325933-B1 | Method for the enhancement of enzyme activities and synthetic efficiency in microorganisms and higher plants | SCHERING AG (DE) | 1994-03-09 | — | — | EP | disclosed |
| EP-0354945-A1 | PROCESS FOR THE ENHANCEMENT OF ENZYME ACTIVITIES AND SYNTHETIC EFFICIENCY IN MICROORGANISMS AND HIGHER PLANTS. | SCHERING AG (DE) | 1990-02-21 | — | — | EP | disclosed |
| EP-0325933-A1 | Method for the enhancement of enzyme activities and synthetic efficiency in microorganisms and higher plants | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-08-02 | — | — | EP | disclosed |
| WO-1989006687-A1 | PROCESS FOR ACTIVATING ENZYMES AND PROMOTING SYNTHESIS IN ORGANISMS | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-07-27 | — | — | WO | disclosed |