Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 9/20 | 0.57 |
| ▸ | ERN1 | O75460 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | TTR | P02766 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1283748 | 0.82 | GPR35 (0.64) | GPR35ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL4144580 | 0.81 | ERN1 (0.69) | GPR35ERN1ALDH1A1MEN1KMT2A | |
| SCHEMBL1479104 | 0.78 | GPR35 (0.59) | GPR35ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL590156 | 0.78 | GPR35 (0.59) | GPR35ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL69964 | 0.78 | GPR35 (0.59) | GPR35ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL11211745 | 0.77 | GPR35 (0.52) | GPR35ERN1ALDH1A1MEN1KMT2A | |
| SCHEMBL9859737 | 0.77 | CYP1A2 (0.50) | GPR35ERN1ALDH1A1MEN1KMT2A | |
| SCHEMBL17744644 | 0.77 | GPR35 (0.52) | GPR35ERN1ALDH1A1MEN1KMT2A | |
| SCHEMBL17744319 | 0.77 | GPR35 (0.50) | GPR35ERN1ALDH1A1MEN1KMT2A | |
| SCHEMBL9112380 | 0.76 | GPR35 (0.83) | GPR35ALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5360932-A | Process for reducing aromatic halo-dinitro-diols in the presence of hydrogen halide | THE DOW CHEMICAL COMPANY (US) | 1994-11-01 | — | — | US | disclosed |
| EP-0484404-A4 | AQUEOUS REDUCTION PROCESS FOR HALO-NITRO-PHENOLS | — | 1992-07-01 | — | — | EP | disclosed |
| EP-0484404-A1 | AQUEOUS REDUCTION PROCESS FOR HALO-NITRO-PHENOLS | THE DOW CHEMICAL COMPANY (US) | 1992-05-13 | — | — | EP | disclosed |
| US-5001265-A | Aqueous reduction process for halo-nitro-phenols | THE DOW CHEMICAL COMPANY (US) | 1991-03-19 | — | — | US | disclosed |
| WO-1991001967-A1 | AQUEOUS REDUCTION PROCESS FOR HALO-NITRO-PHENOLS | THE DOW CHEMICAL COMPANY (US) | 1991-02-21 | — | — | WO | disclosed |