N,N-Diallyl-2-Chloroacetamide

N,N-Diallyl-2-Chloroacetamide

SCHEMBL9328331

C=CCN(CC=C)C(=O)CCl.NCC(=O)O

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D

The experimentally established mechanism targets of N,N-Diallyl-2-Chloroacetamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.48
GLRA1 P23415 1/20 0.39
SLC6A9 P48067 1/20 0.39
OR51E2 Q9H255 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
POLB P06746 1/20 0.35
TSHR P16473 1/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
DPP4 P27487 1/20 0.31
SLC6A2 P23975 2/20 0.31
SLC6A4 P31645 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
N,N-Diallyl-2-Chloroacetamide SCHEMBL4886939 0.88 ALDH1A1 (0.60) ALDH1A1SMN1; SMN2POLBTSHRMEN1
N,N-Diallyl-2-Chloroacetamide SCHEMBL53540 0.88 ALDH1A1 (0.60) ALDH1A1SMN1; SMN2POLBTSHRMEN1
N,N-Diallyl-2-Chloroacetamide SCHEMBL8953543 0.86 ALDH1A1 (0.58) ALDH1A1SMN1; SMN2POLBMEN1NPC1
N,N-Diallyl-2-Chloroacetamide SCHEMBL20819425 0.86 ALDH1A1 (0.58) ALDH1A1SMN1; SMN2POLBMEN1NPC1
SCHEMBL10926107 0.81 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2POLBMEN1NPC1
SCHEMBL2343049 0.79 ALDH1A1 (0.60) ALDH1A1GLRA1SLC6A9OR51E2SMN1; SMN2
Hydrochloric Acid SCHEMBL2339831 0.77 ALDH1A1 (0.58) ALDH1A1SMN1; SMN2POLBMEN1RAB9A
N,N-Diallyl-2-Chloroacetamide SCHEMBL9011296 0.77 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2POLBTSHRMEN1
N,N-Diallyl-2-Chloroacetamide SCHEMBL11811703 0.77 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2POLB
N,N-Diallyl-2-Chloroacetamide SCHEMBL11811713 0.76 ALDH1A1 (0.41) ALDH1A1SMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0584204-A1 MARINE COMPOSITIONS BEARING PREFERENTIALLY CONCENTRATED DOMAINS OF NON-TIN, ORGANO ANTI-FOULING AGENTS BATTELLE MEMORIAL INSTITUTE (US) 1994-03-02 EP claimed
WO-1992020747-A1 MARINE COMPOSITIONS BEARING PREFERENTIALLY CONCENTRATED DOMAINS OF NON-TIN, ORGANO ANTI-FOULING AGENTS BATTELLE MEMORIAL INSTITUTE (US) 1992-11-26 WO claimed
EP-0449975-A1 NON-TIN-BASED, LOW TOXICITY ANTI-FOULING AGENTS. BATTELLE MEMORIAL INSTITUTE (US) 1991-10-09 EP claimed