2,3,6-Trichlorobenzoic Acid

2,3,6-Trichlorobenzoic Acid

SCHEMBL9328359

O=C(O)c1c(Cl)ccc(Cl)c1Cl.O=C(O)c1ccc(Cl)c(Cl)c1Cl

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.53
DPP4 P27487 1/20 0.50
ALDH1A1 P00352 4/20 0.44
KDM4E B2RXH2 3/20 0.44
HSD17B10 Q99714 2/20 0.44
TP53 P04637 1/20 0.44
CASP1 P29466 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
CSNK2A2 P19784 1/20 0.41
CSNK2B P67870 1/20 0.41
CSNK2A1 P68400 1/20 0.41
PBRM1 Q86U86 1/20 0.41
CYP1A2 P05177 1/20 0.39
NPC1 O15118 1/20 0.38
POLB P06746 1/20 0.38
MAPT P10636 1/20 0.38
RAB9A P51151 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
LMNA P02545 1/20 0.37
CYP3A4 P08684 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1155024 0.90 DPP4 (0.56) TSHRDPP4ALDH1A1KDM4EHSD17B10
SCHEMBL29886586 0.89 TSHR (0.64) TSHRDPP4ALDH1A1KDM4EHSD17B10
SCHEMBL432644 0.89 TSHR (0.64) TSHRDPP4ALDH1A1KDM4EHSD17B10
Hydrochloric Acid SCHEMBL7707416 0.88 DPP4 (0.54) TSHRDPP4ALDH1A1KDM4EHSD17B10
SCHEMBL10606007 0.87 TSHR (0.61) TSHRDPP4ALDH1A1KDM4EHSD17B10
SCHEMBL8617010 0.87 TSHR (0.61) TSHRDPP4ALDH1A1KDM4EHSD17B10
SCHEMBL27938221 0.87 TSHR (0.61) TSHRDPP4ALDH1A1KDM4EHSD17B10
SCHEMBL27553108 0.87 TSHR (0.61) TSHRDPP4ALDH1A1KDM4EHSD17B10
2,3,6-Trichlorobenzoic Acid SCHEMBL29365114 0.87 DPP4 (0.62) TSHRDPP4ALDH1A1KDM4EHSD17B10
2,3,6-Trichlorobenzoic Acid SCHEMBL117071 0.87 DPP4 (0.62) TSHRDPP4ALDH1A1KDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0584204-A1 MARINE COMPOSITIONS BEARING PREFERENTIALLY CONCENTRATED DOMAINS OF NON-TIN, ORGANO ANTI-FOULING AGENTS BATTELLE MEMORIAL INSTITUTE (US) 1994-03-02 EP claimed
WO-1992020747-A1 MARINE COMPOSITIONS BEARING PREFERENTIALLY CONCENTRATED DOMAINS OF NON-TIN, ORGANO ANTI-FOULING AGENTS BATTELLE MEMORIAL INSTITUTE (US) 1992-11-26 WO claimed
EP-0584204-A1 MARINE COMPOSITIONS BEARING PREFERENTIALLY CONCENTRATED DOMAINS OF NON-TIN, ORGANO ANTI-FOULING AGENTS BATTELLE MEMORIAL INSTITUTE (US) 1994-03-02 EP disclosed
WO-1992020747-A1 MARINE COMPOSITIONS BEARING PREFERENTIALLY CONCENTRATED DOMAINS OF NON-TIN, ORGANO ANTI-FOULING AGENTS BATTELLE MEMORIAL INSTITUTE (US) 1992-11-26 WO disclosed
EP-0449975-A1 NON-TIN-BASED, LOW TOXICITY ANTI-FOULING AGENTS. BATTELLE MEMORIAL INSTITUTE (US) 1991-10-09 EP disclosed