Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.44 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.44 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | FASN | P49327 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9328413 | 1.00 | GRIA1 (0.44) | GRIA1GRIA2GRIA3USP30ESR2 | |
| SCHEMBL15043499 | 0.88 | GRIA1 (0.48) | GRIA1GRIA2GRIA3USP30ESR2 | |
| SCHEMBL9326567 | 0.84 | GRIA1 (0.42) | GRIA1GRIA2GRIA3USP30ESR2 | |
| SCHEMBL9326560 | 0.84 | GRIA1 (0.42) | GRIA1GRIA2GRIA3USP30ESR2 | |
| SCHEMBL9485943 | 0.84 | GRIA2 (0.45) | GRIA1GRIA2GRIA3USP30CYP2C9 | |
| SCHEMBL9485937 | 0.84 | GRIA2 (0.45) | GRIA1GRIA2GRIA3USP30CYP2C9 | |
| SCHEMBL9325765 | 0.82 | GRIA1 (0.41) | GRIA1GRIA2GRIA3USP30ESR2 | |
| SCHEMBL9325768 | 0.82 | GRIA1 (0.41) | GRIA1GRIA2GRIA3USP30ESR2 | |
| SCHEMBL9553143 | 0.81 | GRIA1 (0.44) | GRIA1GRIA2GRIA3USP30ESR2 | |
| SCHEMBL21649122 | 0.81 | GRIA1 (0.46) | GRIA1GRIA2GRIA3USP30ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0392515-B1 | A difluoroalkylcyclohexyl-benzonitrile derivative | CHISSO CORP (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-5053162-A | Liquid crystals with low driving voltage | CHISSO CORPORATION (JP) | 1991-10-01 | — | — | US | disclosed |
| EP-0392515-A1 | A difluoroalkylcyclohexyl-benzonitrile derivative | Chisso Corporation (JP) | 1990-10-17 | — | — | EP | disclosed |