Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.48 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.48 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | FASN | P49327 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9328413 | 0.88 | GRIA1 (0.44) | GRIA1GRIA2GRIA3HSD11B1USP30 | |
| SCHEMBL9328407 | 0.88 | GRIA1 (0.44) | GRIA1GRIA2GRIA3HSD11B1USP30 | |
| SCHEMBL9485937 | 0.84 | GRIA2 (0.45) | GRIA1GRIA2GRIA3HSD11B1USP30 | |
| SCHEMBL9485943 | 0.84 | GRIA2 (0.45) | GRIA1GRIA2GRIA3HSD11B1USP30 | |
| SCHEMBL11520098 | 0.84 | GRIA2 (0.47) | GRIA1GRIA2GRIA3USP30HRH3 | |
| SCHEMBL11520101 | 0.84 | GRIA2 (0.47) | GRIA1GRIA2GRIA3USP30HRH3 | |
| SCHEMBL11618687 | 0.84 | GRIA1 (0.47) | GRIA1GRIA2GRIA3HSD11B1USP30 | |
| SCHEMBL11616336 | 0.81 | GRIA2 (0.45) | GRIA1GRIA2GRIA3USP30HRH3 | |
| SCHEMBL11523115 | 0.80 | GRIA2 (0.44) | GRIA1GRIA2GRIA3USP30HRH3 | |
| SCHEMBL11523121 | 0.80 | GRIA2 (0.44) | GRIA1GRIA2GRIA3USP30HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9617473-B2 | Switch element comprising a liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2017-04-11 | — | — | US | disclosed |
| US-20130155338-A1 | SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-06-20 | — | — | US | disclosed |