Hydrochloric Acid

Hydrochloric Acid

SCHEMBL9328425

CCCCCCCC[n+]1ccc(N(C)C)cc1.[Cl-]

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 known ✓ P08172 2/20 0.53
CHRM1 known ✓ P11229 2/20 0.53
ACHE known ✓ P22303 2/20 0.53
SLC6A2 known ✓ P23975 2/20 0.53
SLC6A3 known ✓ Q01959 2/20 0.53
CHRM3 known ✓ P20309 1/20 0.52
CHKA P35790 2/20 0.78
KDM4A O75164 2/20 0.71
KDM2A Q9Y2K7 2/20 0.71
KMT2A Q03164 3/20 0.62
MEN1 O00255 2/20 0.62
MAPT P10636 2/20 0.62
TP53 P04637 1/20 0.62
CYP1A2 P05177 1/20 0.62
CYP2D6 P10635 1/20 0.62
CYP2C9 P11712 1/20 0.62
CYP2C19 P33261 1/20 0.62
HTT P42858 3/20 0.60
SMN1; SMN2 Q16637 3/20 0.60
LMNA P02545 2/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6115401 1.00 CHKA (0.78) CHKAKDM4AKDM2AKMT2AMEN1
SCHEMBL23016755 0.98 CHKA (0.81) CHKAKDM4AKDM2AKMT2AMEN1
SCHEMBL17817506 0.98 CHKA (0.81) CHKAKDM4AKDM2AKMT2AMEN1
SCHEMBL1108055 0.98 CHKA (0.81) CHKAKDM4AKDM2AKMT2AMEN1
SCHEMBL17817509 0.98 CHKA (0.81) CHKAKDM4AKDM2AKMT2AMEN1
SCHEMBL9329669 0.98 CHKA (0.81) CHKAKDM4AKDM2AKMT2AMEN1
Fluoride Ion SCHEMBL21758539 0.96 CHKA (0.78) CHKAKDM4AKDM2AKMT2AMEN1
Bromide SCHEMBL3039129 0.96 CHKA (0.85) CHKAKDM4AKDM2AKMT2AMEN1
Water SCHEMBL8976694 0.96 CHKA (0.78) CHKAKDM4AKDM2AKMT2AMEN1
Bromide SCHEMBL9674556 0.96 CHKA (0.85) CHKAKDM4AKDM2AKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0398358-B1 Aluminum electroplating method MITSUBISHI PETROCHEMICAL CO (JP) 1994-03-09 EP claimed
US-5041194-A Using low melting mixture of aluminum halide and onium halide of nitrogen-containing compound MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1991-08-20 US claimed
EP-0398358-A2 Aluminum electroplating method MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1990-11-22 EP claimed
EP-0404188-B1 Non-aqueous electrolytic aluminum plating bath composition NISSHIN STEEL CO LTD (JP) 1994-03-16 EP disclosed
EP-0398358-B1 Aluminum electroplating method MITSUBISHI PETROCHEMICAL CO (JP) 1994-03-09 EP disclosed
US-5074973-A Mixed melt containing aluminum halide, nitrogen-heterocyclic halides, additives, organic polymer NISSHIN STEEL CO. LTD. (JP) 1991-12-24 US disclosed
EP-0253838-B1 CATALYTIC METHOD FOR PRODUCING FLUOROAROMATIC COMPOUNDS USING N-SEC-ALKYL PYRIDINIUM SALTS MALLINCKRODT SPECIALTY CHEMICALS COMPANY (US) 1991-08-21 EP disclosed
US-5041194-A Using low melting mixture of aluminum halide and onium halide of nitrogen-containing compound MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1991-08-20 US disclosed
EP-0404188-A1 Non-aqueous electrolytic aluminum plating bath composition NISSHIN STEEL CO., LTD. (JP) 1990-12-27 EP disclosed
US-4973771-A Phase transfer catalysts MALLINCKRODT, INC. (US) 1990-11-27 US disclosed
EP-0398358-A2 Aluminum electroplating method MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1990-11-22 EP disclosed
WO-1987004149-A1 PHASE TRANSFER CATALYSTS MALLINCKRODT, INC. (US) 1987-07-16 WO disclosed