SCHEMBL9328446

SCHEMBL9328446

CC1CC2(CC(C)C(=O)O2)OC1=O

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20510694 0.88
SCHEMBL9674198 0.81 LMNA (0.33)
SCHEMBL9717735 0.77
SCHEMBL14272279 0.77
SCHEMBL8167356 0.70 MAPT (0.34)
SCHEMBL8167354 0.70 MAPT (0.34)
SCHEMBL12440638 0.70 KDM4E (0.36)
SCHEMBL12951354 0.70 KDM4E (0.33)
SCHEMBL10456416 0.69 TSHR (0.33) SMN1; SMN2
SCHEMBL9674677 0.69 CYP3A4 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0359340-B1 Spirodilactam polymers SHELL INT RESEARCH (NL) 1994-03-16 EP disclosed
EP-0359341-B1 1,6-diazaspiro[4,4]nonane-2,7-dione derivatives SHELL INT RESEARCH (NL) 1994-02-16 EP disclosed
EP-0336475-B1 1,6-DIAZASPIRO (4,4)NONANE-2,7-DIONE DERIVATIVES SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1992-12-23 EP disclosed
US-5164470-A Polymer compositions SHELL OIL COMPANY (US) 1992-11-17 US disclosed
US-5149823-A Sulfonamide substituted spirodilactams SHELL OIL COMPANY (US) 1992-09-22 US disclosed
US-5145910-A Ketocarboxylated polymers SHELL OIL COMPANY (US) 1992-09-08 US disclosed
US-5112938-A CYANO- AND CARBOXY-SUBSTITUTED SPIRODILACTAMS SHELL OIL COMPANY (US) 1992-05-12 US disclosed
US-5103001-A SPIRODILACTAMS SHELL OIL COMPANY (US) 1992-04-07 US disclosed
US-5093499-A Spirodilactam derivatives SHELL OIL COMPANY (US) 1992-03-03 US disclosed
US-5093500-A Spirodilactam bisimides SHELL OIL COMPANY (US) 1992-03-03 US disclosed
US-4968812-A Spirolactonelactams SHELL OIL COMPANY (US) 1990-11-06 US disclosed
US-4940801-A Spirodilactam derivatives SHELL OIL COMPANY (US) 1990-07-10 US disclosed
US-4939251-A Novel spirolactones SHELL OIL COMPANY (US) 1990-07-03 US disclosed
US-4939270-A Spirodilactam diamines SHELL OIL COMPANY (US) 1990-07-03 US disclosed
US-4927906-A Novel polyamideimide polymers SHELL OIL COMPANY (US) 1990-05-22 US disclosed
US-4914176-A Poly(heterocyclic) polymers SHELL OIL COMPANY (US) 1990-04-03 US disclosed
EP-0359341-A2 1,6-diazaspiro[4,4]nonane-2,7-dione derivatives SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1990-03-21 EP disclosed
EP-0359340-A2 Spirodilactam polymers SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1990-03-21 EP disclosed
US-4908458-A 1,5-Di(benzoheterocyclic)-3-oxopentane derivatives SHELL OIL COMPANY (US) 1990-03-13 US disclosed
US-4885351-A Spirodilactam derivatives SHELL OIL COMPANY (US) 1989-12-05 US disclosed