Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | PLA2G4B | P0C869 | 7/20 | 0.55 |
| ▸ | RARB | P10826 | 5/20 | 0.52 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CTRC | Q99895 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9328682 | 0.91 | TP53 (0.50) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL9329257 | 0.90 | TP53 (0.55) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL2255421 | 0.89 | TP53 (0.59) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL8133487 | 0.89 | TP53 (0.59) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL28349098 | 0.89 | TP53 (0.59) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL9327394 | 0.88 | KMT2A (0.53) | TP53TSHRPLA2G4BRARBHTT | |
| SCHEMBL11589038 | 0.87 | TP53 (0.56) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL11617518 | 0.87 | CTRC (0.52) | TSHRCTRC | |
| SCHEMBL11577652 | 0.87 | CTRC (0.52) | TSHRCTRC | |
| SCHEMBL10378989 | 0.86 | TP53 (0.56) | TP53TSHRPLA2G4BRARBPLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368912-B1 | POLYANHYDRIDES WITH IMPROVED HYDROLYTIC DEGRADATION PROPERTIES | MASSACHUSETTS INST TECHNOLOGY (US) | 1994-03-16 | — | — | EP | disclosed |
| EP-0368912-A4 | POLYANHYDRIDES WITH IMPROVED HYDROLYTIC DEGRADATION PROPERTIES | — | 1990-12-19 | — | — | EP | disclosed |
| EP-0368912-A1 | POLYANHYDRIDES WITH IMPROVED HYDROLYTIC DEGRADATION PROPERTIES. | MASSACHUSETTS INST TECHNOLOGY (US) | 1990-05-23 | — | — | EP | disclosed |
| US-4857311-A | FROM P-CARBOXYPHEN(-OXY OR -YL)ALKANOIC ACID; BIODEGRADABLE | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1989-08-15 | — | — | US | disclosed |
| WO-1989000855-A1 | POLYANHYDRIDES WITH IMPROVED HYDROLYTIC DEGRADATION PROPERTIES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1989-02-09 | — | — | WO | disclosed |