Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KLK7 | P49862 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3231393 | 0.86 | HTT (0.63) | KMT2AHTTALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL7562503 | 0.85 | KMT2A (0.52) | KMT2AHTTALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL6261030 | 0.81 | TSHR (0.53) | KMT2AALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL3231401 | 0.81 | KMT2A (0.58) | KMT2AHTTALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL31613156 | 0.79 | ALDH1A1 (0.64) | KMT2AHTTALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL4644036 | 0.79 | KMT2A (0.56) | KMT2AHTTALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL7387748 | 0.79 | HTT (0.56) | KMT2AHTTALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL13012117 | 0.79 | HTT (0.59) | KMT2AHTTALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL10052143 | 0.79 | ELANE (0.40) | KMT2AALDH1A1CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL313139 | 0.78 | HTT (0.69) | KMT2AHTTALDH1A1CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1290648-A | — | — | None | — | — | JP | disclosed |
| EP-0349676-B1 | Tylosin derivatives and process for producing the same | MERCIAN CORP (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-4933439-A | Tylosin derivatives and processes for producing the same | SANRAKU INCORPORATED (JP) | 1990-06-12 | — | — | US | disclosed |
| JP-H01290648-A | P-METHOXYPHENYLACETIC ACID PIVALIC ACID ANHYDRIDE | SANRAKU INC | 1989-11-22 | — | — | JP | disclosed |