Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 4/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | CHRNB1 | P11230 | 3/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.41 |
| ▸ | CHRNB3 | Q05901 | 3/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9656452 | 1.00 | CHRNB2 (0.41) | CHRNB2CHRNA7CHRNA4CHRNB1CHRNB4 | |
| SCHEMBL9656446 | 1.00 | CHRNB2 (0.41) | CHRNB2CHRNA7CHRNA4CHRNB1CHRNB4 | |
| SCHEMBL9328846 | 1.00 | CHRNB2 (0.41) | CHRNB2CHRNA7CHRNA4CHRNB1CHRNB4 | |
| SCHEMBL9656460 | 1.00 | CHRNB2 (0.41) | CHRNB2CHRNA7CHRNA4CHRNB1CHRNB4 | |
| SCHEMBL9492862 | 0.79 | CHRNB2 (0.43) | CHRNB2CHRNA7CHRNA4CHRNB1CHRNB4 | |
| SCHEMBL9490227 | 0.79 | CHRNB2 (0.43) | CHRNB2CHRNA7CHRNA4CHRNB1CHRNB4 | |
| SCHEMBL9490122 | 0.79 | CHRNB2 (0.43) | CHRNB2CHRNA7CHRNA4CHRNB1CHRNB4 | |
| SCHEMBL9491388 | 0.79 | CHRNB2 (0.43) | CHRNB2CHRNA7CHRNA4CHRNB1CHRNB4 | |
| SCHEMBL9655993 | 0.79 | CHRNB2 (0.43) | CHRNB2CHRNA7CHRNA4CHRNB1CHRNB4 | |
| SCHEMBL10586849 | 0.78 | SLC6A4 (0.37) | CHRNB2CHRNA4HCRTR1HCRTR2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321274-B1 | Derivatives of thioformamide | MAY & BAKER LTD (GB) | 1994-03-30 | — | — | EP | disclosed |
| US-5151436-A | Compounds for inhibiting hair loss in men | RHONE-POULENC SANTE (FR) | 1992-09-29 | — | — | US | disclosed |
| EP-0321274-A1 | Derivatives of thioformamide | RHONE POULENC RORER LIMITED (GB) | 1989-06-21 | — | — | EP | disclosed |