Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA known ✓ | P35790 | 4/20 | 0.46 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.52 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.52 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7968644 | 0.98 | SLC22A2 (0.54) | SLC22A2SLC22A1SLC22A3SLC6A4CHKA | |
| Iodide SCHEMBL7968992 | 0.95 | SLC22A2 (0.52) | SLC22A2SLC22A1SLC22A3SLC6A4CHKA | |
| Bromide SCHEMBL483094 | 0.90 | MEN1 (0.52) | SLC22A2SLC22A1SLC22A3SLC6A4CHKA | |
| SCHEMBL1305882 | 0.87 | MEN1 (0.54) | SLC22A2SLC22A1SLC22A3SLC6A4CHKA | |
| Hydrochloric Acid SCHEMBL17504837 | 0.85 | MEN1 (0.52) | SLC22A2SLC22A1SLC22A3SLC6A4CHKA | |
| Iodide SCHEMBL3377972 | 0.85 | KDM4E (0.56) | SLC22A2SLC22A1SLC22A3SLC6A4CHKA | |
| SCHEMBL29201408 | 0.85 | MEN1 (0.52) | SLC22A2SLC22A1SLC22A3SLC6A4CHKA | |
| Bromide SCHEMBL21750926 | 0.84 | KMT2A (0.54) | SLC22A2SLC22A1SLC22A3SLC6A4CHKA | |
| SCHEMBL17933669 | 0.83 | ALDH1A1 (0.68) | CHKAKDM4ERAB9AALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL2463394 | 0.81 | ALDH1A1 (0.71) | CHKAKDM4ERAB9AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0404188-B1 | Non-aqueous electrolytic aluminum plating bath composition | NISSHIN STEEL CO LTD (JP) | 1994-03-16 | — | — | EP | disclosed |
| EP-0339535-B1 | PLATING BATH FOR ELECTRODEPOSITION OF ALUMINUM AND PLATING PROCESS MAKING USE OF THE BATH | NISSHIN STEEL CO., LTD. (JP) | 1993-09-08 | — | — | EP | disclosed |
| US-5074973-A | Mixed melt containing aluminum halide, nitrogen-heterocyclic halides, additives, organic polymer | NISSHIN STEEL CO. LTD. (JP) | 1991-12-24 | — | — | US | disclosed |
| EP-0404188-A1 | Non-aqueous electrolytic aluminum plating bath composition | NISSHIN STEEL CO., LTD. (JP) | 1990-12-27 | — | — | EP | disclosed |
| EP-0339535-A1 | Plating bath for electrodeposition of aluminum and plating process making use of the bath | NISSHIN STEEL CO., LTD. (JP) | 1989-11-02 | — | — | EP | disclosed |