Methacrylic Acid

Methacrylic Acid

SCHEMBL932917

C=C(C)C(=O)O.C=C(C)C(=O)OCCC

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.62
THRB P10828 1/20 0.59
TDP1 Q9NUW8 2/20 0.42
POLB P06746 1/20 0.42
APEX1 P27695 1/20 0.42
HTT P42858 1/20 0.42
ALDH1A1 P00352 6/20 0.41
HCAR2 Q8TDS4 1/20 0.41
GAA P10253 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
LMNA P02545 2/20 0.38
ESR1 P03372 1/20 0.33
CHRM1 P11229 1/20 0.33
SLC6A2 P23975 1/20 0.33
KDR P35968 1/20 0.33
PPM1B O75688 1/20 0.33
PTPN1 P18031 1/20 0.33
PPP1CC P36873 1/20 0.33
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL28367115 1.00 TSHR (0.62) TSHRTHRBTDP1POLBAPEX1
Methacrylic Acid SCHEMBL29001008 0.94 TSHR (0.56) TSHRTHRBTDP1POLBAPEX1
Acetic Acid SCHEMBL21001126 0.93 TSHR (0.64) TSHRTHRBTDP1POLBAPEX1
SCHEMBL21772349 0.93 TSHR (0.69) TSHRTHRBTDP1POLBAPEX1
SCHEMBL16573 0.93
Hydrochloric Acid SCHEMBL31358617 0.91 TSHR (0.67) TSHRTHRBTDP1POLBAPEX1
SCHEMBL31029924 0.91 TSHR (0.67) TSHRTHRBTDP1POLBAPEX1
Hydrochloric Acid SCHEMBL8572537 0.91 TSHR (0.67) TSHRTHRBTDP1POLBAPEX1
SCHEMBL6879356 0.91 TSHR (0.67) TSHRTHRBTDP1POLBAPEX1
SCHEMBL1514196 0.91 TSHR (0.67) TSHRTHRBTDP1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100556963-C The preparation method of polymer coated silica composite particle UNIV WUHAN TECH (CN) 2009-11-04 CN claimed
CN-101089055-A Prepn process of polymer coated silica composite particle UNIV WUHAN TECH (CN) 2007-12-19 CN claimed
US-6083618-A IRRADIATION POLYMERIZABLE; TYPING, WRITING THE GILLETTE COMPANY (US) 2000-07-04 US claimed
EP-0973836-A2 CORRECTION FLUID The Gillette Company (US) 2000-01-26 EP claimed
WO-1998045378-A2 CORRECTION FLUID THE GILLETTE COMPANY (US) 1998-10-15 WO claimed
US-20170333604-A1 READY-MADE BIOMEDICAL DEVICES FOR IN VIVO WELDING YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD (IL) 2017-11-23 US disclosed
US-9526813-B2 Intraluminal polymeric devices for the treatment of aneurysms YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2016-12-27 US disclosed
WO-2016075691-A1 READY-MADE BIOMEDICAL DEVICES FOR IN VIVO WELDING YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD (IL) 2016-05-19 WO disclosed
US-20120179193-A1 INTRALUMINAL POLYMERIC DEVICES FOR THE TREATMENT OF ANEURYSMS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2012-07-12 US disclosed
EP-2453940-A2 INTRALUMINAL POLYMERIC DEVICES FOR THE TREATMENT OF ANEURYSMS Yissum Research Development Company of The Hebrew University of Jerusalem (IL) 2012-05-23 EP disclosed
WO-2011007352-A2 INTRALUMINAL POLYMERIC DEVICES FOR THE TREATMENT OF ANEURYSMS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2011-01-20 WO disclosed
CN-100556963-C The preparation method of polymer coated silica composite particle UNIV WUHAN TECH (CN) 2009-11-04 CN disclosed
WO-1998045378-A2 CORRECTION FLUID THE GILLETTE COMPANY (US) 1998-10-15 WO disclosed
EP-0727981-A1 ANTIPERSPIRANTS AND METHOD OF APPLYING ANTIPERSPIRANT USING A SHAPED ARTICLE THE GILLETTE COMPANY (US) 1996-08-28 EP disclosed
WO-1995013046-A1 ANTIPERSPIRANTS AND METHOD OF APPLYING ANTIPERSPIRANT USING A SHAPED ARTICLE THE GILLETTE COMPANY (US) 1995-05-18 WO disclosed
EP-0425200-B1 Bone cement composition, cured product thereof, implant material and process for the preparation of the same NAKABAYASHI NOBUO (JP) 1994-08-24 EP disclosed
US-5264215-A Polyalkyl methacrylate and hydroxyapatite or copolymers with 4-(methacryloyloxyethyl)trimellitic acid and polymerization catalysts Nakabayashi, Nobuo (JP) 1993-11-23 US disclosed
EP-0425200-A1 Bone cement composition, cured product thereof, implant material and process for the preparation of the same NOBUO NAKABAYASHI (JP) 1991-05-02 EP disclosed
US-4767616-A ACRYLIC ESTER AND AMIDE COPOLYMERS MODIFIED WITH ZWITTERIONS MITSUBISHI YUKA FINE CHEMICALS CO., LTD. (JP) 1988-08-30 US disclosed
US-4020043-A FLUORO-ALIPHATIC-SULFONYL-SUBSTITUTED ETHYLENE COMPOUND MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1977-04-26 US disclosed