Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.67 |
| ▸ | THRB | P10828 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21772349 | 0.98 | TSHR (0.69) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL16573 | 0.98 | — | — | |
| SCHEMBL31029924 | 0.95 | TSHR (0.67) | TSHRTHRBALDH1A1TDP1POLB | |
| Hydrochloric Acid SCHEMBL31358617 | 0.95 | TSHR (0.67) | TSHRTHRBALDH1A1TDP1POLB | |
| Hydrochloric Acid SCHEMBL28868459 | 0.95 | TSHR (0.67) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL1514196 | 0.95 | TSHR (0.67) | TSHRTHRBALDH1A1TDP1POLB | |
| Hydrochloric Acid SCHEMBL8572537 | 0.95 | TSHR (0.67) | TSHRTHRBALDH1A1TDP1POLB | |
| Hydrogen Sulfide SCHEMBL6879353 | 0.95 | TSHR (0.67) | TSHRTHRBALDH1A1TDP1POLB | |
| Potassium SCHEMBL30357416 | 0.95 | TSHR (0.67) | TSHRTHRBALDH1A1TDP1POLB | |
| Lithium SCHEMBL30566726 | 0.95 | TSHR (0.67) | TSHRTHRBALDH1A1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1141124-B1 | ANIONIC-CATIONIC POLYION COMPLEXES COMPRISING ZWITTERIONIC MONOMER COMPONENT | BIOCOMPATIBLES UK LTD (GB) | 2004-02-04 | — | — | EP | disclosed |
| US-20030152547-A1 | Anionic-cationic polyion complexes comprising zwitterionic monomer component | BIOCOMPATIBLES LIMITED | 2003-08-14 | — | — | US | disclosed |
| US-6524569-B1 | Mixing aqueous solutions of overall cationic polymers and overall anionic polymers, at least one of which has pendant zwitterionic groups, to form water swollen gel of polyion complex having improved biocompatibility | BIOCOMPATIBLES UK LIMITED (GB) | 2003-02-25 | — | — | US | disclosed |
| EP-1141124-A1 | ANIONIC-CATIONIC POLYION COMPLEXES COMPRISING ZWITTERIONIC MONOMER COMPONENT | BIOCOMPATIBLES LTD. (GB) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000029481-A1 | ANIONIC-CATIONIC POLYION COMPLEXES COMPRISING ZWITTERIONIC MONOMER COMPONENT | BIOCOMPATIBLES LIMITED (GB) | 2000-05-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030152547-A1 | Anionic-cationic polyion complexes comprising zwitterionic monomer component | PICALM, CLTA, PUF60 | TSHR 3889/4885THRB 4467/4885ALDH1A1 4685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.