Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9328408 | 0.90 | MAPT (0.48) | MAPTNPSR1LMNAHTTGAA | |
| SCHEMBL11553203 | 0.87 | MAPT (0.50) | MAPTNPSR1LMNAHTTGAA | |
| SCHEMBL9657004 | 0.86 | MAPT (0.51) | MAPTLMNAHTTHSD17B10KMT2A | |
| SCHEMBL9307154 | 0.84 | MAPT (0.52) | MAPTNPSR1HTTGAAHSD17B10 | |
| SCHEMBL9307151 | 0.84 | MAPT (0.52) | MAPTNPSR1HTTGAAHSD17B10 | |
| SCHEMBL7913985 | 0.82 | MAPT (0.52) | MAPTNPSR1LMNAHTTGAA | |
| SCHEMBL7913986 | 0.82 | MAPT (0.52) | MAPTNPSR1LMNAHTTGAA | |
| SCHEMBL9331247 | 0.81 | KMT2A (0.52) | MAPTNPSR1HTTGAAHSD17B10 | |
| SCHEMBL9330256 | 0.81 | MAPT (0.51) | MAPTLMNAHTTHSD17B10KMT2A | |
| SCHEMBL9329145 | 0.80 | CYP1A2 (0.47) | MAPTNPSR1LMNAHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0300387-B1 | Phenyl alkenylcarboxylic acids and their esters | BASF AG (DE) | 1994-03-23 | — | — | EP | disclosed |
| EP-0300387-A2 | Phenyl alkenylcarboxylic acids and their esters | BASF Aktiengesellschaft (DE) | 1989-01-25 | — | — | EP | disclosed |