Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9657004 | 0.89 | MAPT (0.51) | MAPTHSD17B10KMT2ACYP1A2CYP2D6 | |
| SCHEMBL9384129 | 0.89 | MAPT (0.56) | MAPTHSD17B10KMT2ACYP1A2CYP2D6 | |
| SCHEMBL9551016 | 0.89 | MAPT (0.56) | MAPTHSD17B10KMT2ACYP1A2CYP2D6 | |
| SCHEMBL9328408 | 0.86 | MAPT (0.48) | MAPTHSD17B10KMT2ACYP1A2CYP2D6 | |
| SCHEMBL9331262 | 0.82 | MAPT (0.52) | MAPTHSD17B10KMT2ACYP1A2CYP2D6 | |
| SCHEMBL9331266 | 0.81 | MAPT (0.53) | MAPTHSD17B10KMT2ACYP1A2CYP2D6 | |
| SCHEMBL9331270 | 0.81 | MAPT (0.53) | MAPTHSD17B10KMT2ACYP1A2CYP2D6 | |
| SCHEMBL9385208 | 0.81 | MAPT (0.53) | MAPTHSD17B10KMT2ACYP1A2CYP2D6 | |
| SCHEMBL10853526 | 0.81 | MAPT (0.53) | MAPTHSD17B10KMT2ACYP1A2CYP2D6 | |
| SCHEMBL9329170 | 0.81 | MAPT (0.48) | MAPTHSD17B10KMT2ACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0300387-B1 | Phenyl alkenylcarboxylic acids and their esters | BASF AG (DE) | 1994-03-23 | — | — | EP | disclosed |
| US-5123955-A | Herbicides, chloro and tetrahydrophthalimido-substituted phenyl | PLATH PETER (DE) | 1992-06-23 | — | — | US | disclosed |
| US-4933001-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1990-06-12 | — | — | US | disclosed |
| EP-0300387-A2 | Phenyl alkenylcarboxylic acids and their esters | BASF Aktiengesellschaft (DE) | 1989-01-25 | — | — | EP | disclosed |