Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8849326 | 0.85 | THRB (0.38) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL3474638 | 0.82 | TSHR (0.35) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL17342020 | 0.82 | TSHR (0.35) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL252308 | 0.80 | TSHR (0.37) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL251451 | 0.79 | TSHR (0.37) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL3474839 | 0.77 | TSHR (0.42) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL3474915 | 0.77 | TSHR (0.42) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL26163344 | 0.77 | TSHR (0.34) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL8854706 | 0.77 | TSHR (0.39) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL67638 | 0.77 | TSHR (0.39) | TSHRKMT2AALDH1A1ESR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0344114-B1 | Unsaturated derivatives of 2,2,6,6-tetramethyl piperidine | CIBA GEIGY AG (CH) | 1994-04-06 | — | — | EP | claimed |
| EP-0344114-A1 | Unsaturated derivatives of 2,2,6,6-tetramethyl piperidine | CIBA-GEIGY AG (CH) | 1989-11-29 | — | — | EP | claimed |