Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 3/20 | 0.44 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 5/20 | 0.42 |
| ▸ | RXRB | P28702 | 5/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 6/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1842790 | 0.80 | RXRA (0.47) | SRD5A2GRIA4RXRARXRBMAPT | |
| SCHEMBL9328518 | 0.77 | RARB (0.50) | SRD5A2GRIA4RXRARXRBRXRG | |
| SCHEMBL9329265 | 0.75 | RARB (0.54) | SRD5A2RXRARXRBMAPTRARB | |
| SCHEMBL9329267 | 0.75 | RARB (0.50) | SRD5A2GRIA4RXRARXRBRXRG | |
| SCHEMBL9329701 | 0.74 | MAPT (0.47) | SRD5A2GRIA4RXRARXRBRXRG | |
| SCHEMBL9329707 | 0.74 | MAPT (0.47) | SRD5A2GRIA4RXRARXRBRXRG | |
| SCHEMBL10519895 | 0.74 | AKR1C2 (0.57) | SRD5A2GRIA4RXRARXRBRXRG | |
| SCHEMBL9328640 | 0.74 | GRIA4 (0.46) | SRD5A2GRIA4RXRARXRBRXRG | |
| SCHEMBL14966540 | 0.73 | KMT2A (0.55) | SRD5A2RXRARXRBRXRGMAPT | |
| SCHEMBL9330512 | 0.73 | RARB (0.65) | MAPTRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332675-A | Liquid crystals | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-07-26 | — | — | US | disclosed |
| EP-0289307-B1 | OPTICALLY ACTIVE AROMATIC CARBOXYLIC ACID DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-07-08 | — | — | EP | disclosed |
| US-5019298-A | Optically active aromatic carboxylic acid derivatives and process for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-05-28 | — | — | US | disclosed |
| EP-0289307-A2 | Optically active aromatic carboxylic acid derivatives and process for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-11-02 | — | — | EP | disclosed |