SCHEMBL9329291

SCHEMBL9329291

CC(=O)OC(C)c1ccc(-c2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.54
RXRA P19793 6/20 0.49
RXRB P28702 5/20 0.49
RXRG P48443 1/20 0.49
GRIA4 P48058 1/20 0.46
PDCD1 Q15116 1/20 0.45
CD274 Q9NZQ7 1/20 0.45
KMT2A Q03164 1/20 0.44
SRD5A2 P31213 1/20 0.44
RARB P10826 1/20 0.44
BCL2L1 Q07817 1/20 0.44
BAD Q92934 1/20 0.44
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA9 Q16790 1/20 0.43
CA14 Q9ULX7 1/20 0.43
MMP12 P39900 1/20 0.42
XDH P47989 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9329056 0.95 KMT2A (0.48) HSD17B10RXRARXRBRXRGKMT2A
SCHEMBL10521081 0.86 PTGS2 (0.56) PDCD1CD274MMP12
SCHEMBL10519895 0.82 AKR1C2 (0.57) HSD17B10RXRARXRBRXRGGRIA4
SCHEMBL9328640 0.82 GRIA4 (0.46) HSD17B10RXRARXRBRXRGGRIA4
SCHEMBL3075285 0.82 KMT2A (0.50) RXRARXRBRXRGKMT2ASRD5A2
SCHEMBL3075291 0.82 KMT2A (0.50) RXRARXRBRXRGKMT2ASRD5A2
SCHEMBL10619308 0.81 FFAR1 (0.42) BCL2L1BADMMP12
SCHEMBL9329080 0.80 CA12 (0.50) PDCD1CD274KMT2ACA12CA1
SCHEMBL9329707 0.80 MAPT (0.47) HSD17B10RXRARXRBRXRGGRIA4
SCHEMBL9329701 0.80 MAPT (0.47) HSD17B10RXRARXRBRXRGGRIA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5332675-A Liquid crystals SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-07-26 US disclosed
EP-0289307-B1 OPTICALLY ACTIVE AROMATIC CARBOXYLIC ACID DERIVATIVES AND PROCESS FOR PRODUCING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-07-08 EP disclosed
US-5019298-A Optically active aromatic carboxylic acid derivatives and process for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-05-28 US disclosed
EP-0289307-A2 Optically active aromatic carboxylic acid derivatives and process for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-11-02 EP disclosed