Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9792615 | 0.92 | MEN1 (0.43) | MEN1KMT2ACYP2C9ALOX15CYP2C19 | |
| Hydrochloric Acid SCHEMBL9330013 | 0.91 | MEN1 (0.42) | MEN1KMT2ACYP2C9ALOX15CYP2C19 | |
| SCHEMBL8525185 | 0.79 | KMT2A (0.41) | MEN1KMT2ACYP2C9ALOX15CYP2C19 | |
| SCHEMBL9329327 | 0.78 | HDAC3 (0.44) | HDAC3HDAC1KDM4EMAP3K5HDAC6 | |
| SCHEMBL9069849 | 0.78 | KMT2A (0.59) | MEN1KMT2ACYP2C9ALOX15CYP2C19 | |
| SCHEMBL3337029 | 0.77 | KDM4E (0.50) | KMT2AHSD17B10HDAC3HDAC1KDM4E | |
| SCHEMBL9329461 | 0.77 | MEN1 (0.48) | MEN1KMT2ACYP2C9ALOX15CYP2C19 | |
| SCHEMBL9328726 | 0.76 | HIF1A (0.54) | MEN1KMT2ACYP2C9ALOX15CYP2C19 | |
| SCHEMBL9331727 | 0.76 | MEN1 (0.50) | MEN1KMT2ACYP2C9ALOX15CYP2C19 | |
| SCHEMBL9329229 | 0.76 | MEN1 (0.47) | MEN1KMT2ACYP2C9ALOX15CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0300400-B1 | Nitric acid ester derivative | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-03-16 | — | — | EP | claimed |
| US-4923886-A | VASODILATORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-05-08 | — | — | US | claimed |
| EP-0300400-A1 | Nitric acid ester derivative | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-01-25 | — | — | EP | claimed |
| JP-2028167-A | — | — | None | — | — | JP | disclosed |
| EP-0300400-B1 | Nitric acid ester derivative | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-5010093-A | Vasodilators; cardiovascular disorders | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-04-23 | — | — | US | disclosed |
| US-4923886-A | VASODILATORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-05-08 | — | — | US | disclosed |
| JP-H0228167-A | NITRIC ACID ESTER DERIVATIVE | FUJISAWA PHARMACEUT CO LTD | 1990-01-30 | — | — | JP | disclosed |
| EP-0300400-A1 | Nitric acid ester derivative | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-01-25 | — | — | EP | disclosed |