Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | FPR3 | P25089 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3337029 | 0.84 | KDM4E (0.50) | HDAC3HDAC1KDM4ESMN1; SMN2MAP3K5 | |
| SCHEMBL9792615 | 0.83 | MEN1 (0.43) | HDAC3HDAC1KDM4EATG4BSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9330013 | 0.82 | MEN1 (0.42) | HDAC3HDAC1KDM4EATG4BSMN1; SMN2 | |
| SCHEMBL3338965 | 0.81 | HDAC3 (0.53) | HDAC3HDAC1KDM4ESMN1; SMN2MAP3K5 | |
| SCHEMBL7107993 | 0.79 | SMN1; SMN2 (0.46) | KDM4EATG4BSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL9329296 | 0.78 | MEN1 (0.49) | HDAC3HDAC1KDM4EATG4BSMN1; SMN2 | |
| SCHEMBL24915784 | 0.78 | HDAC3 (0.53) | HDAC3HDAC1KDM4EMAP3K5HDAC6 | |
| SCHEMBL10708899 | 0.78 | KDM4E (0.52) | HDAC3HDAC1KDM4ESMN1; SMN2MAP3K5 | |
| SCHEMBL29509654 | 0.78 | MAP3K5 (0.50) | HDAC3HDAC1KDM4ESMN1; SMN2MAP3K5 | |
| SCHEMBL19595561 | 0.77 | HDAC3 (0.35) | HDAC3HDAC1KDM4ESMN1; SMN2MAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0300400-B1 | Nitric acid ester derivative | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-5010093-A | Vasodilators; cardiovascular disorders | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-04-23 | — | — | US | disclosed |
| US-4923886-A | VASODILATORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-05-08 | — | — | US | disclosed |
| EP-0300400-A1 | Nitric acid ester derivative | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-01-25 | — | — | EP | disclosed |