Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 12/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28355080 | 0.85 | TAAR1 (0.45) | TSHRCYP2D6HIF1AKDM4EABCB1 | |
| Hydrochloric Acid SCHEMBL11247700 | 0.85 | TSHR (0.57) | TSHRCYP2D6KDM4EATM | |
| Hydrochloric Acid SCHEMBL11247706 | 0.85 | TSHR (0.57) | TSHRCYP2D6KDM4EATM | |
| SCHEMBL22518483 | 0.83 | CYP2D6 (0.43) | TSHRCYP2D6HIF1AKDM4EABCB1 | |
| Hydrochloric Acid SCHEMBL11252787 | 0.83 | SLC18A3 (0.56) | — | |
| Hydrochloric Acid SCHEMBL11252780 | 0.83 | SLC18A3 (0.56) | — | |
| SCHEMBL6549925 | 0.80 | ABCB1 (0.57) | TSHRCYP2D6HIF1AKDM4EABCB1 | |
| SCHEMBL6549930 | 0.80 | ABCB1 (0.57) | TSHRCYP2D6HIF1AKDM4EABCB1 | |
| SCHEMBL6548872 | 0.79 | ABCB1 (0.55) | TSHRCYP2D6HIF1AKDM4EABCB1 | |
| Hydrochloric Acid SCHEMBL11266253 | 0.78 | MAPT (0.64) | TSHRCYP2D6KDM4ERAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328906-A | 0-(3-amino-2-hydroxypropyl)-hydroximic acid halides and process for preparing the same | BIOREX KUTATO-FEJLESZTO KFT (HU) | 1994-07-12 | — | — | US | disclosed |
| US-5296606-A | O-(3-amino-2-hydroxypropyl)-hydroximic acid halides and process for preparing the same | BIOREX KUTATO-FEJLESZTO KFT (HU) | 1994-03-22 | — | — | US | disclosed |
| EP-0417210-B1 | NOVEL O-(3-AMINO-2-HYDROXYPROPYL)-HYDROXIMIC ACID HALIDES AND PROCESS FOR PREPARING THE SAME | BIOREX KUTATO FEJLESZTOE KFT (HU) | 1994-03-09 | — | — | EP | disclosed |
| US-5147879-A | O-(3-AMINO-2-HYDROXYPROPYL)-HYDROXIMIC ACID HALIDES AND PROCESS FOR PREPARING THE SAME | BIOREX KUTATO-FEJLESZTO KFT (HU) | 1992-09-15 | — | — | US | disclosed |
| WO-1990004584-A1 | NOVEL O-(3-AMINO-2-HYDROXYPROPYL)-HYDROXIMIC ACID HALIDES AND PROCESS FOR PREPARING THE SAME | BIOREX KUTATÓ FEJLESZTO^' KFT. (HU) | 1990-05-03 | — | — | WO | disclosed |