Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.40 |
| ▸ | KYNU | Q16719 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 5/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7742452 | 0.79 | ALDH1A1 (0.43) | ALDH1A1GLATSHRTP53NPC1 | |
| SCHEMBL7747749 | 0.76 | ALDH1A1 (0.52) | ALDH1A1GLATSHRTP53NPC1 | |
| SCHEMBL3809800 | 0.75 | ALDH1A1 (0.46) | ALDH1A1GLATSHRTP53NPC1 | |
| SCHEMBL9330076 | 0.75 | ALDH1A1 (0.43) | ALDH1A1GLATSHRTP53NPC1 | |
| SCHEMBL9662182 | 0.75 | ALDH1A1 (0.43) | ALDH1A1GLATSHRTP53NPC1 | |
| SCHEMBL9330080 | 0.75 | ALDH1A1 (0.43) | ALDH1A1GLATSHRTP53NPC1 | |
| SCHEMBL10547387 | 0.73 | ATM (0.38) | SLC1A3SLC1A2SLC1A1ALDH1A1GLA | |
| SCHEMBL7746415 | 0.73 | TP53 (0.70) | ALDH1A1GLATSHRTP53NPC1 | |
| SCHEMBL7746733 | 0.72 | ALDH1A1 (0.43) | ALDH1A1GLATSHRTP53NPC1 | |
| SCHEMBL3915161 | 0.70 | MEN1 (0.44) | PKMALDH1A1GLATSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0225634-B1 | Antibacterial compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-04-06 | — | — | EP | disclosed |
| US-4946837-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-08-07 | — | — | US | disclosed |
| US-4839351-A | Antibacterial compounds, and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-06-13 | — | — | US | disclosed |
| US-4826834-A | BACTERICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-05-02 | — | — | US | disclosed |
| US-4788185-A | Cephalosporin compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-11-29 | — | — | US | disclosed |
| EP-0229369-A2 | Cephalosporins, process for their preparation and pharmaceutical compositions containing them | Takeda Chemical Industries, Ltd. (JP) | 1987-07-22 | — | — | EP | disclosed |
| EP-0225634-A2 | Antibacterial compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-06-16 | — | — | EP | disclosed |
| US-4665065-A | 3-pyrazolo(1,5-aαpyridinium cephem compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-05-12 | — | — | US | disclosed |
| EP-0160252-A2 | Antibacterial compounds | Takeda Chemical Industries, Ltd. (JP) | 1985-11-06 | — | — | EP | disclosed |