Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | RXRA | P19793 | 5/20 | 0.55 |
| ▸ | RXRB | P28702 | 5/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.50 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 1/20 | 0.46 |
| ▸ | RARG | P13631 | 1/20 | 0.46 |
| ▸ | CDC25A | P30304 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 2/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1098811 | 0.93 | TDP1 (0.54) | TDP1RXRARXRBCDC25ACDC25B | |
| SCHEMBL29393207 | 0.93 | TDP1 (0.54) | TDP1RXRARXRBCDC25ACDC25B | |
| SCHEMBL29361914 | 0.91 | TDP1 (0.56) | TDP1RXRARXRBSRD5A2CDC25A | |
| SCHEMBL105948 | 0.91 | TDP1 (0.56) | TDP1RXRARXRBSRD5A2CDC25A | |
| SCHEMBL29441322 | 0.91 | TDP1 (0.56) | TDP1RXRARXRBSRD5A2CDC25A | |
| SCHEMBL267196 | 0.89 | TDP1 (0.54) | TDP1RXRARXRBCDC25ACDC25B | |
| SCHEMBL11023998 | 0.88 | TDP1 (0.59) | TDP1RXRARXRBSRD5A2CDC25A | |
| SCHEMBL8579977 | 0.87 | ALDH1A1 (0.52) | TDP1RXRARXRBCDC25ACDC25B | |
| SCHEMBL9789238 | 0.87 | TDP1 (0.50) | TDP1RXRARXRBRXRGHSD17B10 | |
| Bisphenol A SCHEMBL31517147 | 0.85 | TDP1 (0.60) | TDP1RXRARXRBSRD5A2CDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0359340-B1 | Spirodilactam polymers | SHELL INT RESEARCH (NL) | 1994-03-16 | — | — | EP | disclosed |
| US-4927906-A | Novel polyamideimide polymers | SHELL OIL COMPANY (US) | 1990-05-22 | — | — | US | disclosed |
| EP-0359340-A2 | Spirodilactam polymers | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-03-21 | — | — | EP | disclosed |