Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.76 |
| ▸ | MAOB | P27338 | 2/20 | 0.72 |
| ▸ | PTGES | O14684 | 3/20 | 0.69 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.67 |
| ▸ | MET | P08581 | 7/20 | 0.65 |
| ▸ | CA12 | O43570 | 4/20 | 0.65 |
| ▸ | CA4 | P22748 | 4/20 | 0.65 |
| ▸ | CA6 | P23280 | 4/20 | 0.65 |
| ▸ | CA5A | P35218 | 4/20 | 0.65 |
| ▸ | CA7 | P43166 | 4/20 | 0.65 |
| ▸ | CA9 | Q16790 | 4/20 | 0.65 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.65 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.65 |
| ▸ | APP | P05067 | 2/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9329895 | 1.00 | TTR (0.76) | TTRMAOBPTGESEPHX2MET | |
| SCHEMBL9333279 | 0.91 | TTR (0.64) | TTRMAOBPTGESEPHX2MET | |
| SCHEMBL9333276 | 0.91 | TTR (0.64) | TTRMAOBPTGESEPHX2MET | |
| SCHEMBL30302461 | 0.90 | PTGES (0.73) | TTRMAOBPTGESEPHX2MET | |
| SCHEMBL29145012 | 0.90 | PTGES (0.73) | TTRMAOBPTGESEPHX2MET | |
| SCHEMBL18585756 | 0.90 | PTGES (0.73) | TTRMAOBPTGESEPHX2MET | |
| SCHEMBL18010096 | 0.89 | PTGES (0.70) | TTRMAOBPTGESALOX5NFE2L2 | |
| SCHEMBL16692678 | 0.89 | PTGES (0.77) | TTRMAOBPTGESAPPALOX5 | |
| SCHEMBL16692689 | 0.89 | PTGES (0.70) | TTRMAOBPTGESALOX5NFE2L2 | |
| SCHEMBL18010087 | 0.89 | PTGES (0.77) | TTRMAOBPTGESAPPALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0380669-B1 | ISOPRENOID DERIVATIVES AND PHARMACEUTICAL PREPARATION CONTAINING SAME | TERUMO CORP (JP) | 1994-03-23 | — | — | EP | disclosed |
| US-5130483-A | Antiulcer agents and enzyme inhibitors | TERUMO KABUSHIKI KAISHA (JP) | 1992-07-14 | — | — | US | disclosed |
| EP-0380669-A1 | ISOPRENOID DERIVATIVES AND PHARMACEUTICAL PREPARATION CONTAINING SAME | TERUMO KABUSHIKI KAISHA (JP) | 1990-08-08 | — | — | EP | disclosed |