Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | APOL1 | O14791 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28896874 | 0.79 | EPHX1 (0.39) | PRCPEPHX1BCHEGAAALDH1A1 | |
| SCHEMBL9330344 | 0.79 | MEN1 (0.36) | PRCPEPHX1BCHEMEN1KMT2A | |
| SCHEMBL9330739 | 0.76 | BCHE (0.38) | PRCPBCHEGAASMN1; SMN2EPHX2 | |
| SCHEMBL27508951 | 0.75 | MEN1 (0.40) | PRCPMEN1KMT2ABLMSMN1; SMN2 | |
| SCHEMBL24507877 | 0.74 | EPHX1 (0.56) | EPHX1BCHEGAAKCNA3CHRNB2 | |
| SCHEMBL13372835 | 0.74 | CHRM1 (0.39) | PRCPEPHX1BCHEMEN1KMT2A | |
| SCHEMBL27999966 | 0.74 | CHRM1 (0.39) | PRCPEPHX1BCHEMEN1KMT2A | |
| SCHEMBL2904411 | 0.74 | CHRM3 (0.44) | EPHX1BCHEGAAKCNA3CHRNB2 | |
| SCHEMBL11751691 | 0.73 | EPHX1 (0.65) | EPHX1GAAKCNA3ALDH1A1SMN1; SMN2 | |
| SCHEMBL21582234 | 0.71 | PRCP (0.64) | PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366004-B1 | Cyclic azaaliphatic compounds with a nitroxy group, process for their preparation and pharmaceutical compositions thereof | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-30 | — | — | EP | disclosed |
| EP-0366004-A1 | Cyclic azaaliphatic compounds with a nitroxy group, process for their preparation and pharmaceutical compositions thereof | Roche Diagnostics GmbH (DE) | 1990-05-02 | — | — | EP | disclosed |