Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.39 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.39 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | APOL1 | O14791 | 1/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.34 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.34 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8482146 | 0.87 | TDP1 (0.45) | CHRM3EPHX1TPSAB1TPSD1TPSG1 | |
| SCHEMBL29990844 | 0.84 | EPHX1 (0.50) | CHRM3EPHX1TPSAB1TPSD1TPSG1 | |
| SCHEMBL24507877 | 0.83 | EPHX1 (0.56) | EPHX1TPSAB1TPSD1TPSG1KCNA3 | |
| SCHEMBL11751691 | 0.81 | EPHX1 (0.65) | EPHX1KCNA3GAATSHRALOX15 | |
| SCHEMBL28015769 | 0.81 | EPHX1 (0.40) | CHRM3EPHX1TPSAB1TPSD1TPSG1 | |
| SCHEMBL4484094 | 0.81 | GAA (0.58) | EPHX1KCNA3GAAGNAI3GNAO1 | |
| SCHEMBL29991599 | 0.81 | MEN1 (0.46) | CHRM3EPHX1TPSAB1TPSD1TPSG1 | |
| SCHEMBL29991483 | 0.80 | GNAI3 (0.57) | EPHX1GAAGNAI3GNAO1GNAI1 | |
| SCHEMBL2897100 | 0.80 | EPHX1 (0.68) | CHRM3EPHX1TPSAB1TPSD1TPSG1 | |
| SCHEMBL19263958 | 0.79 | EPHX1 (0.45) | CHRM3EPHX1TPSAB1TPSD1TPSG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2212288-A1 | CRYSTALLINE FORM OF PIPERIDINE COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2010-08-04 | — | — | EP | disclosed |
| WO-2009069827-A1 | CRYSTALLINE FORM OF PIPERIDINE COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-06-04 | — | — | WO | disclosed |