Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | CES1 | P23141 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10719391 | 0.87 | NPC1 (0.73) | NPC1KMT2AMEN1SMN1; SMN2HPGD | |
| SCHEMBL11289405 | 0.87 | KMT2A (0.81) | NPC1KMT2AMEN1SMN1; SMN2HPGD | |
| SCHEMBL5706070 | 0.85 | TSHR (0.55) | NPC1KMT2AMAPTKDM4EALOX15 | |
| SCHEMBL11021070 | 0.83 | TSHR (0.76) | NPC1KMT2AMEN1SMN1; SMN2HPGD | |
| Dimethyl Phthalate SCHEMBL27438615 | 0.82 | TSHR (0.71) | KMT2ASMN1; SMN2MAPTKDM4EALOX15 | |
| SCHEMBL8996748 | 0.81 | KMT2A (0.65) | NPC1KMT2AMEN1SMN1; SMN2HPGD | |
| SCHEMBL11170734 | 0.81 | ALDH1A1 (0.57) | KMT2AMAPTKDM4EALOX15TSHR | |
| SCHEMBL8780712 | 0.81 | KMT2A (0.71) | NPC1KMT2AMEN1SMN1; SMN2HPGD | |
| SCHEMBL1898771 | 0.81 | NPC1 (1.00) | NPC1KMT2AMEN1SMN1; SMN2HPGD | |
| SCHEMBL29356203 | 0.81 | NPC1 (1.00) | NPC1KMT2AMEN1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5278218-A | Heat resistance | RHONE-POULENC CHIMIE (FR) | 1994-01-11 | — | — | US | claimed |
| US-5194470-A | Nonyellowing polymer compositions for heat stability | RHONE-POULENC CHIMIE (FR) | 1993-03-16 | — | — | US | claimed |
| US-5143959-A | Mixture of dawsonite, hydrotalcite, polysiloxane and organometallic compound; heat resistant | RHONE-POULENC CHIMIE (FR) | 1992-09-01 | — | — | US | claimed |
| EP-0453380-A1 | Stabilized compositions of halogenated polymers | RHONE-POULENC CHIMIE (FR) | 1991-10-23 | — | — | EP | claimed |
| US-5194470-A | Nonyellowing polymer compositions for heat stability | RHONE-POULENC CHIMIE (FR) | 1993-03-16 | — | — | US | disclosed |
| US-5143959-A | Mixture of dawsonite, hydrotalcite, polysiloxane and organometallic compound; heat resistant | RHONE-POULENC CHIMIE (FR) | 1992-09-01 | — | — | US | disclosed |
| EP-0453380-A1 | Stabilized compositions of halogenated polymers | RHONE-POULENC CHIMIE (FR) | 1991-10-23 | — | — | EP | disclosed |
| EP-0401134-A1 | Coumpounds having a dihydropyridine function | RHONE POULENC CHIMIE (FR) | 1990-12-05 | — | — | EP | disclosed |
| EP-0391811-A1 | Method for stabilizing halogenated polymers | RHONE-POULENC CHIMIE (FR) | 1990-10-10 | — | — | EP | disclosed |
| US-4381360-A | 1,3-Dicarbonyl compounds and polyvinyl halide resin compositions containing the same | PHOENIX CHEMICAL CORPORATION (US) | 1983-04-26 | — | — | US | disclosed |
| EP-0040286-A2 | Polyvinyl halide resin compositions containing 1,3 Dicarbonyl compounds | PHOENIX CHEMICAL CORPORATION (US) | 1981-11-25 | — | — | EP | disclosed |