Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.51 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.51 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.51 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.51 |
| ▸ | KDM5A | P29375 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9433339 | 0.79 | GRIA1 (0.47) | GRIA1GRIA2GRIA3GRIA4KDM5A | |
| SCHEMBL29579885 | 0.77 | CYP1A2 (0.69) | GRIA1GRIA2GRIA3GRIA4KDM4E | |
| SCHEMBL982104 | 0.77 | CYP1A2 (0.69) | GRIA1GRIA2GRIA3GRIA4KDM4E | |
| SCHEMBL8247664 | 0.75 | ADORA3 (0.51) | ALDH1A1MAPTSMN1; SMN2ADORA3ADORA2A | |
| SCHEMBL4036186 | 0.71 | PARP1 (0.42) | KDM5AKDM5BPARP1GABRA5DAO | |
| SCHEMBL2270268 | 0.71 | CYP1A2 (0.60) | KDM5ASMN1; SMN2ADORA3ADORA2AADORA1 | |
| SCHEMBL9432802 | 0.71 | OPRL1 (0.49) | PARP1METAP2DAO | |
| SCHEMBL9106684 | 0.70 | PARP1 (0.65) | ALDH1A1PARP1DAO | |
| SCHEMBL30363017 | 0.70 | PARP1 (0.65) | ALDH1A1PARP1DAO | |
| SCHEMBL8609163 | 0.70 | GRIA1 (0.65) | GRIA1GRIA2GRIA3GRIA4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0589914-A1 | NOVEL 3-FUSED PYRIDINIUMMETHYL CEPHALOSPORINS | CHEIL FOODS & CHEMICALS, INC. (KR) | 1994-04-06 | — | — | EP | disclosed |
| US-5281589-A | Pharmaceuticals | CHEIL FOODS & CHEMICALS, INC. (KR) | 1994-01-25 | — | — | US | disclosed |
| WO-1992022556-A1 | NOVEL 3-FUSED PYRIDINIUMMETHYL CEPHALOSPORINS | CHEIL FOODS & CHEMICALS, INC. (KR) | 1992-12-23 | — | — | WO | disclosed |