Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 17/20 | 0.65 |
| ▸ | ADRB1 | P08588 | 16/20 | 0.65 |
| ▸ | ADRB2 | P07550 | 7/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9330483 | 0.99 | ADRB3 (0.66) | ADRB3ADRB1ADRB2CYP1A2CYP3A4 | |
| SCHEMBL9329788 | 0.90 | ADRB1 (0.67) | ADRB3ADRB1ADRB2CYP1A2CYP3A4 | |
| SCHEMBL10347028 | 0.88 | ADRB1 (0.78) | ADRB3ADRB1ADRB2CYP1A2CYP3A4 | |
| SCHEMBL8758078 | 0.88 | ADRB3 (0.77) | ADRB3ADRB1ADRB2CYP1A2 | |
| SCHEMBL9332316 | 0.88 | ADRB3 (0.77) | ADRB3ADRB1ADRB2CYP1A2 | |
| SCHEMBL9330113 | 0.87 | ADRB3 (0.67) | ADRB3ADRB1ADRB2CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL9330163 | 0.87 | ADRB1 (0.76) | ADRB3ADRB1ADRB2CYP1A2 | |
| Hydrochloric Acid SCHEMBL9330095 | 0.87 | ADRB1 (0.76) | ADRB3ADRB1ADRB2CYP1A2 | |
| Hydrochloric Acid SCHEMBL9330165 | 0.87 | CYP3A4 (0.65) | ADRB3ADRB1ADRB2CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL9330115 | 0.86 | ADRB3 (0.67) | ADRB3ADRB1ADRB2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328251-B1 | 2-(2-Hydroxy-3-phenoxypropylamino)ethylphenoxyacetamides and processes and intermediates for their preparation | ICI PLC (GB) | 1994-04-13 | — | — | EP | disclosed |
| US-4999377-A | 2-(2-hydroxy-3-phenoxypropylamino)ethylphenoxyacetamide compounds; dietetics | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-03-12 | — | — | US | disclosed |
| EP-0328251-A2 | 2-(2-Hydroxy-3-phenoxypropylamino)ethylphenoxyacetamides and processes and intermediates for their preparation | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-08-16 | — | — | EP | disclosed |