Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9329839 | 0.84 | HDAC8 (0.48) | HDAC8KDM4ESMN1; SMN2NPC1RAB9A | |
| Fluoride Ion SCHEMBL18740631 | 0.82 | HDAC8 (0.46) | HDAC8KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL9332458 | 0.76 | HDAC8 (0.41) | HDAC8KDM4ESMN1; SMN2HTTACHE | |
| SCHEMBL11430745 | 0.75 | KDM4E (0.37) | KDM4ESMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL10266294 | 0.72 | HDAC8 (0.41) | HDAC8KDM4ESMN1; SMN2ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL663764 | 0.71 | HDAC8 (0.40) | HDAC8ALDH1A1MAPTKMT2AACHE | |
| Iodide SCHEMBL28265270 | 0.71 | GAA (0.42) | HDAC8KDM4ESMN1; SMN2RAB9AMEN1 | |
| SCHEMBL9330218 | 0.70 | HDAC8 (0.36) | HDAC8KDM4ESMN1; SMN2RAB9AMEN1 | |
| Iodide SCHEMBL28830448 | 0.69 | HDAC8 (0.39) | HDAC8ALDH1A1MAPTACHETSHR | |
| SCHEMBL26077634 | 0.69 | HDAC8 (0.53) | HDAC8ACHETSHRHRH1PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0440784-B1 | PREPARATION OF DI-CATION ETHERS | EASTMAN KODAK CO (US) | 1994-04-13 | — | — | EP | disclosed |
| US-5110937-A | PREPARATION OF DI-CATION ETHERS | EASTMAN KODAK COMPANY (US) | 1992-05-05 | — | — | US | disclosed |