Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | NQO1 | P15559 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10266294 | 0.98 | HDAC8 (0.41) | HDAC8GAAALDH1A1LTA4HNQO1 | |
| Iodide SCHEMBL28265270 | 0.96 | GAA (0.42) | HDAC8GAAALDH1A1LTA4HNQO1 | |
| Iodide SCHEMBL28830448 | 0.94 | HDAC8 (0.39) | HDAC8GAAALDH1A1LTA4HNQO1 | |
| Iodide SCHEMBL28830447 | 0.92 | GAA (0.40) | HDAC8GAAALDH1A1LTA4HNQO1 | |
| SCHEMBL11089214 | 0.90 | GAA (0.37) | HDAC8GAAALDH1A1LTA4HNQO1 | |
| SCHEMBL11089211 | 0.87 | HDAC8 (0.38) | HDAC8GAAALDH1A1LTA4HNQO1 | |
| SCHEMBL13265051 | 0.80 | LTA4H (0.44) | HDAC8LTA4HTSHRL3MBTL1 | |
| SCHEMBL7066274 | 0.77 | LTA4H (0.43) | ALDH1A1LTA4HTSHRKMT2AMAPT | |
| SCHEMBL4748895 | 0.76 | L3MBTL1 (0.44) | HDAC8GAATSHRMAPTL3MBTL1 | |
| SCHEMBL11430745 | 0.75 | KDM4E (0.37) | GAAALDH1A1LTA4HNQO1RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4190588-A1 | TIRE BEAD INSULATION CONTAINING MALEIMIDE | The Goodyear Tire & Rubber Company (US) | 2023-06-07 | — | — | EP | disclosed |
| US-8142101-B2 | Hydrocarbon-adsorbing porous pavement structure | Reynolds Presto Products Inc. (US) | 2012-03-27 | — | — | US | disclosed |
| US-8137024-B2 | Hydrocarbon-adsorbing porous pavement structure | Reynolds Presto Products Inc. (US) | 2012-03-20 | — | — | US | disclosed |
| US-20120045280-A1 | HYDROCARBON-ADSORBING POROUS PAVEMENT STRUCTURE | REYNOLDS CONSUMER PRODUCTS, INC. D/B/A PRESTO PRODUCTS COMPANY (US) | 2012-02-23 | — | — | US | disclosed |
| US-8043982-B2 | Basalt particle-containing compositions and articles for protective coatings and ballistic shield mats/tiles/protective building components | U.S. WIND FARMING, INC. (US) | 2011-10-25 | — | — | US | disclosed |
| US-8025456-B2 | Hydrocarbon-adsorbing porous pavement structure | REYNOLDS CONSUMER PRODUCTS, INC. (US) | 2011-09-27 | — | — | US | disclosed |
| US-20100285269-A1 | BASALT PARTICLE-CONTAINING COMPOSITIONS AND ARTICLES FOR PROTECTIVE COATINGS AND BALLISTIC SHIELD MATS/TILES/PROTECTIVE BUILDING COMPONENTS | U.S. WIND FARMING, INC. (US) | 2010-11-11 | — | — | US | disclosed |
| EP-2193237-A1 | HYDROCARBON-ADSORBING POROUS PAVEMENT STRUCTURE | Reynolds Consumer Products, Inc. (US) | 2010-06-09 | — | — | EP | disclosed |
| US-20100012004-A1 | Basalt particle-containing compositions and articles for protective coatings and ballistic shield mats/tiles/protective building components | U.S. WIND FARMING INC. (US) | 2010-01-21 | — | — | US | disclosed |
| US-20090067924-A1 | HYDROCARBON-ADSORBING POROUS PAVEMENT STRUCTURE | KAUL CORPORATION (US) | 2009-03-12 | — | — | US | disclosed |
| US-6969737-B2 | Adhesion promoter for cord-reinforced rubber and metal or polymer substrate/rubber composites | THE C.P. HALL COMPANY (US) | 2005-11-29 | — | — | US | disclosed |
| US-20050194752-A1 | Joint assemblies, methods for installing joint assemblies, and jointing compositions | BANK OF AMERICA, N.A., AS AGENT | 2005-09-08 | — | — | US | disclosed |
| WO-2005061646-A1 | ADHESION PROMOTERS FOR SEALANTS | CPH INNOVATIONS CORPORATION (US) | 2005-07-07 | — | — | WO | disclosed |
| WO-2005056707-A1 | ADHESION PROMOTERS FOR CORD-REINFORCED THERMOPLASTIC POLYMERIC MATERIALS AND SUBSTRATE/THERMOPLASTIC POLYMERIC MATERIAL COMPOSITES | CPH INNOVATIONS CORPORATION (US) | 2005-06-23 | — | — | WO | disclosed |
| US-6884832-B2 | Adhesion promoter for cord-reinforced rubber and metal or polymer substrate/rubber composites | THE C.P. HALL COMPANY (US) | 2005-04-26 | — | — | US | disclosed |
| US-20040127616-A1 | Liquid form ester/resin adhesion promoter | THE C.P. HALL COMPANY | 2004-07-01 | — | — | US | disclosed |
| US-20040122145-A1 | Adhesion promoters for sealants | THE C.P. HALL COMPANY | 2004-06-24 | — | — | US | disclosed |
| US-20040002564-A1 | Adhesion promoter for cord-reinforced rubber and metal or polymer substrate/rubber composites | BANK OF AMERICA, N.A., AS AGENT | 2004-01-01 | — | — | US | disclosed |
| US-20030220426-A1 | Adhesion promoter for cord-reinforced rubber and metal or polymer substrate/rubber composites | BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT | 2003-11-27 | — | — | US | disclosed |
| US-20030220427-A1 | Adhesion promoter for cord-reinforced rubber and metal or polymer substrate/rubber composites | CPH INNOVATIONS CORP. | 2003-11-27 | — | — | US | disclosed |