SCHEMBL9330338

SCHEMBL9330338

CN1CCCC(O[N+](=O)[O-])C1

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.45
HTT P42858 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
CYP2D6 P10635 2/20 0.39
POLB P06746 1/20 0.39
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
ATM Q13315 1/20 0.37
CHRM2 P08172 1/20 0.35
CHRM1 P11229 1/20 0.35
CHRM3 P20309 1/20 0.35
ALDH1A1 P00352 1/20 0.35
CYP3A4 P08684 1/20 0.35
GSR P00390 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9333378 0.78 SMN1; SMN2 (0.44) SMN1; SMN2HTTL3MBTL1CYP2D6POLB
SCHEMBL4889799 0.76 GSR (0.39) CYP2D6MEN1KMT2ACHRM2CHRM1
SCHEMBL9344103 0.73 ALDH1A1 (0.42) MEN1KMT2AATMALDH1A1
SCHEMBL324551 0.73
SCHEMBL14499693 0.73
SCHEMBL3436862 0.71
SCHEMBL8241010 0.71
SCHEMBL356233 0.71
SCHEMBL27970973 0.71 SMN1; SMN2 (0.34) SMN1; SMN2HTTL3MBTL1CYP2D6KMT2A
SCHEMBL3804843 0.71 GSR (0.54) POLBMEN1KMT2AALDH1A1GSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0338599-A2 Diesel fuel composition ETHYL CORPORATION (US) 1989-10-25 EP claimed
EP-0195462-A2 Diesel fuel composition ETHYL CORPORATION (US) 1986-09-24 EP claimed
EP-0101093-A2 Diesel fuel composition ETHYL CORPORATION (US) 1984-02-22 EP claimed
US-4405334-A 1-ALKYLPIPERIDINOL NITRATE ESTER ANTIKNOCK ADDITIVE ETHYL CORPORATION (US) 1983-09-20 US claimed
EP-0366004-B1 Cyclic azaaliphatic compounds with a nitroxy group, process for their preparation and pharmaceutical compositions thereof BOEHRINGER MANNHEIM GMBH (DE) 1994-03-30 EP disclosed
US-5280031-A Cyclic azaaliphatic compounds with a nitroxy function, processes for the preparation thereof and pharmaceutical compositions containing them BOEHRINGER MANNHEIM GMBH (DE) 1994-01-18 US disclosed
US-5258049-A Nitric acid esters of phenylethanol ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1993-11-02 US disclosed
US-5030641-A Treatment of angina pectoris, hypotensive agents BOEHRINGER MANNHEIM GMBH (DE) 1991-07-09 US disclosed
EP-0366004-A1 Cyclic azaaliphatic compounds with a nitroxy group, process for their preparation and pharmaceutical compositions thereof Roche Diagnostics GmbH (DE) 1990-05-02 EP disclosed
EP-0338599-A2 Diesel fuel composition ETHYL CORPORATION (US) 1989-10-25 EP disclosed
EP-0195462-A2 Diesel fuel composition ETHYL CORPORATION (US) 1986-09-24 EP disclosed
EP-0101093-A2 Diesel fuel composition ETHYL CORPORATION (US) 1984-02-22 EP disclosed
US-4405334-A 1-ALKYLPIPERIDINOL NITRATE ESTER ANTIKNOCK ADDITIVE ETHYL CORPORATION (US) 1983-09-20 US disclosed