SCHEMBL933041

SCHEMBL933041

CCCC#Cc1cn([C@@H]2CC(O)[C@H](CO)O2)c(=O)[nH]c1=O

nearest known ligand 0.68

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TK1 P04183 3/20 0.66
TK2 O00142 1/20 0.66
LMNA P02545 2/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
ALOX12 P18054 1/20 0.58
ADRA1A P35348 1/20 0.58
CYP1A2 P05177 1/20 0.56
CYP3A4 P08684 1/20 0.56
TSHR P16473 1/20 0.56
BLM P54132 1/20 0.56
PMP22 Q01453 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL933039 1.00 TK1 (0.66) TK1TK2LMNASMN1; SMN2ALOX12
Phosphoric Acid SCHEMBL8600183 0.96 TK1 (0.61) TK1TK2LMNASMN1; SMN2ALOX12
SCHEMBL21585108 0.94 TK1 (0.63) TK1TK2LMNASMN1; SMN2ALOX12
SCHEMBL3931463 0.94 TK1 (0.63) TK1TK2LMNASMN1; SMN2ALOX12
SCHEMBL3931456 0.94 TK1 (0.63) TK1TK2LMNASMN1; SMN2ALOX12
SCHEMBL7166566 0.93 TK1 (0.62) TK1TK2LMNASMN1; SMN2ALOX12
SCHEMBL7166563 0.93 TK1 (0.62) TK1TK2LMNASMN1; SMN2ALOX12
SCHEMBL4263815 0.92 TK1 (0.61) TK1TK2LMNASMN1; SMN2ALOX12
SCHEMBL7172039 0.92 TK1 (0.61) TK1TK2LMNASMN1; SMN2ALOX12
SCHEMBL7170550 0.92 TK1 (0.61) TK1TK2LMNASMN1; SMN2ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3149167-B1 APTAMER TARGETING MAGE-A3 PEPTIDE AND USES THEREOF ACADEMIA SINICA (TW) 2019-09-04 EP claimed
US-9976146-B2 Aptamer targeting MAGE-A3 peptide and uses thereof IANALYZER INCORPORATION (TW) 2018-05-22 US claimed
US-20170183660-A1 APTAMER TARGETING MAGE-A3 PEPTIDE AND USES THEREOF ACADEMIA SINICA (TW) 2017-06-29 US claimed
EP-3149167-A1 APTAMER TARGETING MAGE-A3 PEPTIDE AND USES THEREOF Academia Sinica (TW) 2017-04-05 EP claimed
WO-2015184224-A1 APTAMER TARGETING MAGE-A3 PEPTIDE AND USES THEREOF ACADEMIA SINICA (TW) 2015-12-03 WO claimed
US-12098370-B2 Method for generating aptamers with improved off-rates SOMALOGIC OPERATING CO., INC. (US) 2024-09-24 US disclosed
CN-118064441-A Methods of producing aptamers with improved dissociation rates 私募蛋白质体运营有限公司 2024-05-24 CN disclosed
CN-109415723-B Improved promoters and compositions 牛津大学创新有限公司 2024-04-19 CN disclosed
US-20220090080-A1 Method for Generating Aptamers with Improved Off-Rates SOMALOGIC, INC. (US) 2022-03-24 US disclosed
US-11111495-B2 Method for generating aptamers with improved off-rates SOMALOGIC, INC. (US) 2021-09-07 US disclosed
US-20190330634-A1 Method for Generating Aptamers with Improved Off-Rates SOMALOGIC OPERATING CO., INC. 2019-10-31 US disclosed
EP-3149167-B1 APTAMER TARGETING MAGE-A3 PEPTIDE AND USES THEREOF ACADEMIA SINICA (TW) 2019-09-04 EP disclosed
US-5763208-A Oligonucleotides and their analogs capable of passive cell membrane permeation GILEAD SCIENCES, INC. (US) 1998-06-09 US disclosed
US-5756291-A IDENTIFYING OLIGOMER SEQUENCES; QUALITATIVE ANALYSIS; ANALYSIS OF THROMBIN BY COMPLEXING GILEAD SCIENCES, INC. (US) 1998-05-26 US disclosed
WO-1998016661-A2 MORPHATIDES: NOVEL SHAPE AND STRUCTURE LIBRARIES MORPHAGEN (US) 1998-04-23 WO disclosed
WO-1998004575-A2 LIPOPHILIC OLIGONUCLEOTIDE ANALOGS GILEAD SCIENCES, INC. (US) 1998-02-05 WO disclosed
US-5633360-A CONTAINS AT LEAST TWO NUCLEOSIDE RESIDUES AND INTERNUCLEOTIDE LINKAGES GILEAD SCIENCES, INC. (US) 1997-05-27 US disclosed
EP-0572529-A1 APTAMER SPECIFIC FOR BIOMOLECULES AND METHOD OF MAKING GILEAD SCIENCES, INC. (US) 1993-12-08 EP disclosed
WO-1992014842-A1 APTAMERS SPECIFIC FOR THROMBIN AND METHODS OF USE GILEAD SCIENCES, INC. (US) 1992-09-03 WO disclosed
WO-1992014843-A1 APTAMER SPECIFIC FOR BIOMOLECULES AND METHOD OF MAKING GILEAD SCIENCES, INC. (US) 1992-09-03 WO disclosed