Morpholine

Morpholine

SCHEMBL9330481

C1COCCN1.CCC(N)OC(=O)c1cc2ccccc2cc1O

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.41
MAPT P10636 10/20 0.41
KMT2A Q03164 6/20 0.40
MEN1 O00255 5/20 0.40
ALDH1A1 P00352 4/20 0.40
NPSR1 Q6W5P4 3/20 0.40
KDM4E B2RXH2 3/20 0.40
HTT P42858 2/20 0.40
GAA P10253 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
LMNA P02545 2/20 0.40
MITF O75030 1/20 0.39
NCOA1 Q15788 1/20 0.39
NCOA3 Q9Y6Q9 1/20 0.39
MAPK1 P28482 3/20 0.39
POLB P06746 2/20 0.39
NPC1 O15118 1/20 0.39
APOBEC3A P31941 1/20 0.39
RAB9A P51151 1/20 0.39
APOBEC3G Q9HC16 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Morpholine SCHEMBL5162361 0.83 NPC1 (0.48) SMN1; SMN2MAPTKMT2AMEN1KDM4E
Morpholine SCHEMBL10436290 0.82 NPC1 (0.33) MAPTKMT2AMEN1ALDH1A1KDM4E
Morpholine SCHEMBL11135140 0.77 MEN1 (0.43) MAPTKMT2AMEN1ALDH1A1NPSR1
SCHEMBL9330470 0.76 KDM4E (0.44) MAPTKMT2ANPSR1KDM4EHTT
SCHEMBL6231650 0.69 CA12 (0.60) SMN1; SMN2MAPTKMT2AMEN1ALDH1A1
Morpholine SCHEMBL8196429 0.68 MEN1 (0.32) KMT2AMEN1KDM4EGAACYP2C9
SCHEMBL30125169 0.66 KMT2A (0.67) SMN1; SMN2MAPTKMT2AMEN1ALDH1A1
SCHEMBL3303791 0.66 KMT2A (0.67) SMN1; SMN2MAPTKMT2AMEN1ALDH1A1
SCHEMBL10594875 0.66 MAPT (0.49) SMN1; SMN2MAPTKMT2AMEN1ALDH1A1
SCHEMBL28280196 0.65 SMN1; SMN2 (0.47) SMN1; SMN2MAPTKMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0352122-B1 Heat development type diazo copying material FUJI PHOTO FILM CO LTD (JP) 1994-03-23 EP disclosed
EP-0123224-B1 HEAT SENSITIVE RECORDING MATERIALS FUJI PHOTO FILM CO., LTD. (JP) 1988-06-29 EP disclosed
EP-0123224-A2 Heat sensitive recording materials FUJI PHOTO FILM CO., LTD. (JP) 1984-10-31 EP disclosed