Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16889196 | 0.78 | CRBN (0.33) | CRBNBRD4CREBBPKDM4ELMNA | |
| SCHEMBL28316310 | 0.78 | KDM4E (0.34) | CRBNBRD4CREBBPKDM4ELMNA | |
| SCHEMBL1169368 | 0.69 | SMN1; SMN2 (0.56) | KDM4ELMNATSHR | |
| SCHEMBL26660615 | 0.65 | CRBN (0.33) | CRBNBRD4CREBBPKDM4ELMNA | |
| SCHEMBL19438354 | 0.64 | CRBN (0.52) | CRBNBRD4CREBBPKDM4ELMNA | |
| SCHEMBL16885266 | 0.63 | CRBN (0.31) | CRBN | |
| SCHEMBL21244594 | 0.63 | BRD4 (0.34) | CRBNBRD4 | |
| SCHEMBL26793110 | 0.63 | CRBN (0.31) | CRBN | |
| SCHEMBL28315276 | 0.62 | CRBN (0.39) | CRBNBRD4CREBBPKDM4ELMNA | |
| SCHEMBL4559467 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0359340-B1 | Spirodilactam polymers | SHELL INT RESEARCH (NL) | 1994-03-16 | — | — | EP | disclosed |
| US-5034504-A | Spirodilactam polyamide polymer | SHELL OIL COMPANY (US) | 1991-07-23 | — | — | US | disclosed |
| US-4968770-A | Polyamide from spirodilactam precursor and primary diamine | SHELL OIL COMPANY (US) | 1990-11-06 | — | — | US | disclosed |
| EP-0359340-A2 | Spirodilactam polymers | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-03-21 | — | — | EP | disclosed |
| US-4908458-A | 1,5-Di(benzoheterocyclic)-3-oxopentane derivatives | SHELL OIL COMPANY (US) | 1990-03-13 | — | — | US | disclosed |