Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 3/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 4/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 4/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9330357 | 0.90 | GAA (0.47) | CHRM3EPHX1GAASCN1ASCN2A | |
| SCHEMBL8484303 | 0.88 | TDP1 (0.46) | CHRM3EPHX1GAASCN1ASCN2A | |
| SCHEMBL14420642 | 0.83 | EPHX1 (0.66) | CHRM3EPHX1GAASCN1ASCN2A | |
| SCHEMBL9333184 | 0.82 | CHRM3 (0.55) | CHRM3EPHX1GAA | |
| SCHEMBL9333182 | 0.81 | SMN1; SMN2 (0.55) | EPHX1MEN1KMT2AALDH1A1ATM | |
| SCHEMBL24507877 | 0.80 | EPHX1 (0.56) | EPHX1GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL9332538 | 0.80 | CYP2D6 (0.40) | CHRM3EPHX1GAAMEN1KMT2A | |
| SCHEMBL11751691 | 0.79 | EPHX1 (0.65) | EPHX1GAAALDH1A1KCNA3SMN1; SMN2 | |
| SCHEMBL9333430 | 0.78 | CHRM3 (0.38) | CHRM3EPHX1GAASCN1ASCN2A | |
| SCHEMBL30916849 | 0.77 | CHRM3 (0.49) | CHRM3SCN1ASCN2ASCN3AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366004-B1 | Cyclic azaaliphatic compounds with a nitroxy group, process for their preparation and pharmaceutical compositions thereof | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-30 | — | — | EP | disclosed |
| EP-0366004-A1 | Cyclic azaaliphatic compounds with a nitroxy group, process for their preparation and pharmaceutical compositions thereof | Roche Diagnostics GmbH (DE) | 1990-05-02 | — | — | EP | disclosed |