Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 6/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.40 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.39 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.39 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9330357 | 0.94 | GAA (0.47) | TDP1GAACHRM3EPHX1KEAP1 | |
| SCHEMBL9330666 | 0.88 | CHRM3 (0.47) | GAACHRM3EPHX1MEN1KMT2A | |
| SCHEMBL8482511 | 0.81 | ACHE (0.56) | GAAACHEEPHX1 | |
| SCHEMBL8482146 | 0.79 | TDP1 (0.45) | TDP1GAACHRM3ACHEEPHX1 | |
| SCHEMBL14420642 | 0.78 | EPHX1 (0.66) | GAACHRM3EPHX1MEN1KMT2A | |
| SCHEMBL14165270 | 0.77 | TDP1 (0.44) | TDP1GAAACHEEPHX1 | |
| SCHEMBL9330460 | 0.77 | GAA (0.40) | GAACHRM3EPHX1KEAP1NFE2L2 | |
| SCHEMBL8480272 | 0.76 | BCHE (0.63) | ACHE | |
| SCHEMBL13368228 | 0.75 | GNAI3 (0.52) | GAAKMT2A | |
| SCHEMBL29372143 | 0.74 | EPHX1 (0.61) | TDP1GAAEPHX1TPSAB1TPSD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952506-A | Process for the synthesis of 4- 6- (hexylcarbamoyloxy) hexylcarbamoyloxy!-piperidine-1-carboxylic acid 4-phenoxyphenyl ester | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-09-14 | — | — | US | claimed |
| WO-1998047870-A1 | PROCESS FOR THE SYNTHESIS OF 4-[6-(HEXYLCARBAMOYLOXY) HEXYLCARBAMOYLOXY]-PIPERIDINE-1- CARBOXYLIC ACID 4-PHENOXYPHENYL ESTER | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-10-29 | — | — | WO | claimed |