Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 7/20 | 0.67 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.67 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.67 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.67 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.67 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.67 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.67 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.67 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.67 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.67 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.67 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.67 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 3/20 | 0.52 |
| ▸ | TTR | P02766 | 1/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9332495 | 0.99 | PTGES (0.66) | PTGESHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9332503 | 0.99 | PTGES (0.66) | PTGESHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9332489 | 0.99 | PTGES (0.66) | PTGESHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL18585756 | 0.92 | PTGES (0.73) | PTGESHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL30302461 | 0.92 | PTGES (0.73) | PTGESHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29145012 | 0.92 | PTGES (0.73) | PTGESHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9333279 | 0.90 | TTR (0.64) | PTGESHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9333276 | 0.90 | TTR (0.64) | PTGESHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9330292 | 0.89 | PTGES (0.70) | PTGESHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9332519 | 0.89 | PTGES (0.70) | PTGESHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0380669-B1 | ISOPRENOID DERIVATIVES AND PHARMACEUTICAL PREPARATION CONTAINING SAME | TERUMO CORP (JP) | 1994-03-23 | — | — | EP | disclosed |
| US-5130483-A | Antiulcer agents and enzyme inhibitors | TERUMO KABUSHIKI KAISHA (JP) | 1992-07-14 | — | — | US | disclosed |
| EP-0380669-A1 | ISOPRENOID DERIVATIVES AND PHARMACEUTICAL PREPARATION CONTAINING SAME | TERUMO KABUSHIKI KAISHA (JP) | 1990-08-08 | — | — | EP | disclosed |