Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9333237 | 0.93 | SMN1; SMN2 (0.47) | SMN1; SMN2HTTL3MBTL1CYP2D6POLB | |
| SCHEMBL9330460 | 0.85 | GAA (0.40) | GAAMEN1KMT2ABCHEEPHX1 | |
| SCHEMBL9348885 | 0.81 | TSHR (0.50) | HTTGAAKMT2ABCHE | |
| SCHEMBL9332542 | 0.80 | BCHE (0.37) | SMN1; SMN2POLBKMT2ABCHEEPHX1 | |
| SCHEMBL9330747 | 0.80 | SMN1; SMN2 (0.43) | SMN1; SMN2HTTL3MBTL1CYP2D6POLB | |
| SCHEMBL9333182 | 0.79 | SMN1; SMN2 (0.55) | SMN1; SMN2HTTL3MBTL1CYP2D6POLB | |
| SCHEMBL9333430 | 0.78 | CHRM3 (0.38) | SMN1; SMN2GAAMEN1KMT2ABCHE | |
| SCHEMBL9329952 | 0.77 | SMN1; SMN2 (0.45) | SMN1; SMN2HTTL3MBTL1CYP2D6POLB | |
| SCHEMBL9330739 | 0.73 | BCHE (0.38) | SMN1; SMN2GAABCHE | |
| SCHEMBL9329947 | 0.72 | MEN1 (0.35) | MEN1KMT2ABCHEEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366004-B1 | Cyclic azaaliphatic compounds with a nitroxy group, process for their preparation and pharmaceutical compositions thereof | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-30 | — | — | EP | disclosed |
| EP-0366004-A1 | Cyclic azaaliphatic compounds with a nitroxy group, process for their preparation and pharmaceutical compositions thereof | Roche Diagnostics GmbH (DE) | 1990-05-02 | — | — | EP | disclosed |