Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 5/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MLNR | O43193 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9333430 | 0.92 | CHRM3 (0.38) | GAABCHECHRM3EPHX1MEN1 | |
| SCHEMBL9330841 | 0.85 | SMN1; SMN2 (0.48) | GAABCHEEPHX1MEN1KMT2A | |
| SCHEMBL9330164 | 0.81 | CHRM3 (0.46) | GAABCHECHRM3EPHX1TMEM97 | |
| SCHEMBL9330357 | 0.79 | GAA (0.47) | GAACHRM3EPHX1KEAP1NFE2L2 | |
| SCHEMBL9332542 | 0.79 | BCHE (0.37) | BCHEEPHX1TMEM97KMT2A | |
| SCHEMBL9333237 | 0.78 | SMN1; SMN2 (0.47) | EPHX1MEN1KMT2AALDH1A1 | |
| SCHEMBL9333436 | 0.78 | CHRM3 (0.36) | CHRM3MEN1KMT2ASCN1ASCN2A | |
| SCHEMBL8484303 | 0.77 | TDP1 (0.46) | GAACHRM3EPHX1KEAP1NFE2L2 | |
| SCHEMBL9333382 | 0.77 | MEN1 (0.36) | BCHEEPHX1TMEM97MEN1KMT2A | |
| SCHEMBL9330666 | 0.76 | CHRM3 (0.47) | GAACHRM3EPHX1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366004-B1 | Cyclic azaaliphatic compounds with a nitroxy group, process for their preparation and pharmaceutical compositions thereof | BOEHRINGER MANNHEIM GMBH (DE) | 1994-03-30 | — | — | EP | disclosed |
| EP-0366004-A1 | Cyclic azaaliphatic compounds with a nitroxy group, process for their preparation and pharmaceutical compositions thereof | Roche Diagnostics GmbH (DE) | 1990-05-02 | — | — | EP | disclosed |