Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL873423 | 0.77 | — | — | |
| SCHEMBL12249888 | 0.73 | SMN1; SMN2 (0.33) | ATAD2NOTUM | |
| SCHEMBL22238000 | 0.72 | NOTUM (0.38) | ATAD2NOTUM | |
| SCHEMBL16921631 | 0.72 | NOTUM (0.38) | ATAD2NOTUM | |
| SCHEMBL15491101 | 0.70 | CSNK2A1 (0.50) | NOTUM | |
| SCHEMBL8434325 | 0.68 | NOTUM (0.43) | ATAD2NOTUMATM | |
| SCHEMBL8871377 | 0.68 | ATAD2 (0.32) | ATAD2 | |
| SCHEMBL20844176 | 0.67 | — | — | |
| SCHEMBL13818944 | 0.65 | NOTUM (0.44) | ATAD2NOTUMATM | |
| SCHEMBL1538363 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292885-A | Pyranone, process for its preparation, its use in the preparation of a new pyridinone and a process for the preparation of same | ISOCHEM (FR) | 1994-03-08 | — | — | US | claimed |
| US-5292885-A | Pyranone, process for its preparation, its use in the preparation of a new pyridinone and a process for the preparation of same | ISOCHEM (FR) | 1994-03-08 | — | — | US | disclosed |
| US-5292885-A | Pyranone, process for its preparation, its use in the preparation of a new pyridinone and a process for the preparation of same | ISOCHEM (FR) | 1994-03-08 | — | — | US | disclosed |
| EP-0412892-A1 | Pyranon, process for its preparation, its application for the preparation of a pyridon and preparation process for the latter | ISOCHEM (FR) | 1991-02-13 | — | — | EP | disclosed |