Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GLI1 | P08151 | 1/20 | 0.40 |
| ▸ | GLI2 | P10070 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11453690 | 0.95 | PTGS1 (0.45) | PTGS1MEN1CYP2D6KMT2AALOX5 | |
| SCHEMBL2179193 | 0.82 | AOC3 (0.49) | ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL27973467 | 0.82 | PTGS1 (0.56) | PTGS1MEN1CYP2D6KMT2AALOX5 | |
| SCHEMBL8768529 | 0.82 | KCNA3 (0.50) | KMT2AALOX5LTA4HTSHRALDH1A1 | |
| SCHEMBL19065075 | 0.81 | MAOB (0.55) | MEN1KMT2AALOX5MAOBTSHR | |
| SCHEMBL11996670 | 0.81 | PTGS1 (0.58) | PTGS1MEN1CYP2D6KMT2AALOX5 | |
| SCHEMBL7949292 | 0.80 | PTGS1 (0.62) | PTGS1MEN1CYP2D6KMT2AALOX5 | |
| SCHEMBL9774444 | 0.80 | PTGS1 (0.56) | PTGS1MEN1CYP2D6KMT2AALOX5 | |
| SCHEMBL9526801 | 0.79 | PTGS1 (0.53) | PTGS1MEN1CYP2D6KMT2AALOX5 | |
| SCHEMBL10728247 | 0.79 | LMNA (0.60) | PTGS1MEN1CYP2D6KMT2AALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355800-B1 | Process for the preparation of aryl-dimethyl-3-arylpropyl-silanes | HOECHST AG (DE) | 1994-04-20 | — | — | EP | disclosed |
| EP-0240121-B1 | DIPHENYL ETHER DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-04-17 | — | — | EP | disclosed |
| EP-0240121-A2 | Diphenyl ether derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-10-07 | — | — | EP | disclosed |