Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | PPOX | P50336 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.43 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.43 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8693586 | 0.91 | MEN1 (0.47) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL8693593 | 0.89 | MEN1 (0.50) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL9134954 | 0.87 | TDP1 (0.50) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL9331767 | 0.86 | TDP1 (0.47) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11039095 | 0.84 | HSPB1 (0.48) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL9199456 | 0.84 | MEN1 (0.50) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11014034 | 0.83 | TDP1 (0.51) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL9331754 | 0.82 | NR4A1 (0.44) | CYP3A4MAPTCYP1A2CYP2C19LMNA | |
| SCHEMBL10806230 | 0.82 | KMT2A (0.57) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10830663 | 0.82 | MEN1 (0.46) | TDP1MEN1KMT2ATTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0448206-B1 | Substituted benzimidazole and indazole derivatives, processes for their preparation and their use as herbicides | ZENECA LTD (GB) | 1994-12-28 | — | — | EP | disclosed |
| US-5306692-A | Herbicidal indazole and benzimidazole compounds | ZENECA LIMITED (GB) | 1994-04-26 | — | — | US | disclosed |
| EP-0448206-A2 | Substituted benzimidazole and indazole derivatives, processes for their preparation and their use as herbicides | ZENECA LIMITED (GB) | 1991-09-25 | — | — | EP | disclosed |