Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 8/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9331523 | 1.00 | BCHE (0.45) | BCHELMNAHTR1ADRD3MAPK1 | |
| SCHEMBL9759641 | 0.86 | BCHE (0.39) | BCHEACHE | |
| SCHEMBL9759648 | 0.86 | BCHE (0.39) | BCHEACHE | |
| SCHEMBL439056 | 0.84 | BCHE (0.56) | BCHEHTR1ADRD3ACHEPTGS1 | |
| SCHEMBL9759495 | 0.82 | LMNA (0.43) | BCHELMNAHTR1ADRD3MAPK1 | |
| SCHEMBL9331439 | 0.81 | LMNA (0.46) | BCHELMNAHTR1ADRD3MAPK1 | |
| SCHEMBL9331442 | 0.81 | LMNA (0.46) | BCHELMNAHTR1ADRD3MAPK1 | |
| SCHEMBL9331534 | 0.79 | LMNA (0.46) | BCHELMNAHTR1ADRD3MAPK1 | |
| SCHEMBL9759761 | 0.78 | LMNA (0.43) | BCHELMNAHTR1ADRD3MAPK1 | |
| SCHEMBL9759757 | 0.78 | LMNA (0.43) | BCHELMNAHTR1ADRD3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5321026-A | Antispasmodic agents | RHONE-POULENC RORER S.A. (FR) | 1994-06-14 | — | — | US | disclosed |
| US-5049669-A | Also diuretics | RHONE-POULENC SANTE (FR) | 1991-09-17 | — | — | US | disclosed |
| US-4985419-A | Analgesics, Diuretics | RHONE-POULENC SANTE (FR) | 1991-01-15 | — | — | US | disclosed |
| US-4912105-A | Derivatives of phenothiazine and the compositions which contain them | RHONE-POULENC SANTE (FR) | 1990-03-27 | — | — | US | disclosed |