Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | POLA1 | P09884 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ACP1 | P24666 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9796874 | 0.88 | MAPT (0.51) | GAAKMT2APOLA1MAPK1TSHR | |
| SCHEMBL10939456 | 0.85 | GAA (0.63) | GAAKMT2APOLA1MAPK1TSHR | |
| SCHEMBL9332428 | 0.84 | DYRK1A (0.71) | GAAKMT2AMAPK1NPSR1ALDH1A1 | |
| SCHEMBL4861743 | 0.82 | GAA (0.62) | GAAKMT2APOLA1MAPK1TSHR | |
| SCHEMBL9332450 | 0.82 | GAA (0.62) | GAAKMT2APOLA1MAPK1TSHR | |
| SCHEMBL30754208 | 0.82 | DYRK1A (0.71) | GAAKMT2APOLA1MAPK1TSHR | |
| SCHEMBL8354836 | 0.81 | GAA (0.61) | GAAKMT2APOLA1MAPK1TSHR | |
| SCHEMBL7932269 | 0.81 | GAA (0.61) | GAAKMT2APOLA1MAPK1TSHR | |
| SCHEMBL24804597 | 0.81 | RAB9A (0.62) | GAAPOLA1MAPK1TSHRALDH1A1 | |
| SCHEMBL4858670 | 0.79 | GAA (0.58) | GAAKMT2APOLA1MAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0397169-B1 | Novel benzothiazole derivatives | TOYO BOSEKI (JP) | 1994-04-13 | — | — | EP | claimed |
| US-5036086-A | Novel benzothiazole derivatives | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1991-07-30 | — | — | US | claimed |
| EP-0397169-A1 | Novel benzothiazole derivatives | TOYO BOSEKI KABUSHIKI KAISHA Trading under the name of Toyobo Co., Ltd. (JP) | 1990-11-14 | — | — | EP | claimed |
| EP-0397169-B1 | Novel benzothiazole derivatives | TOYO BOSEKI (JP) | 1994-04-13 | — | — | EP | disclosed |
| US-5036086-A | Novel benzothiazole derivatives | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1991-07-30 | — | — | US | disclosed |
| EP-0397169-A1 | Novel benzothiazole derivatives | TOYO BOSEKI KABUSHIKI KAISHA Trading under the name of Toyobo Co., Ltd. (JP) | 1990-11-14 | — | — | EP | disclosed |