Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19409326 | 0.84 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL29198317 | 0.80 | TSHR (0.60) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL1019850 | 0.78 | TSHR (0.58) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL3349590 | 0.78 | TSHR (0.58) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL2958968 | 0.78 | TSHR (0.44) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL10627157 | 0.78 | TSHR (0.58) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL31019197 | 0.77 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5144090 | 0.77 | TSHR (0.79) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL25426 | 0.77 | TSHR (0.79) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL182045 | 0.77 | TSHR (0.72) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279414-B1 | Rubber composition and the use thereof for the production of an oil seal or a rubber hose | JAPAN SYNTHETIC RUBBER CO LTD (JP) | 1994-05-04 | — | — | EP | disclosed |
| US-5171787-A | Blends; high strength, heat, cold and oil resistance | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1992-12-15 | — | — | US | disclosed |
| US-5010137-A | Blend with polyorganohydrogensiloxane, transition metal compound | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1991-04-23 | — | — | US | disclosed |
| EP-0405461-A2 | Silicone-based composite rubber composition and uses thereof | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1991-01-02 | — | — | EP | disclosed |
| EP-0279414-A2 | Rubber composition and the use thereof for the production of an oil seal or a rubber hose | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1988-08-24 | — | — | EP | disclosed |