Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELP | P16109 | 3/20 | 0.39 |
| ▸ | TLR4 | O00206 | 8/20 | 0.36 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.34 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SYNJ2 | O15056 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9332998 | 0.89 | SELP (0.34) | SELPSIRT2SIRT1MEN1ALDH1A1 | |
| SCHEMBL9332055 | 0.84 | TLR4 (0.46) | TLR4 | |
| SCHEMBL6795477 | 0.82 | SELP (0.45) | SELPTLR4LGALS8 | |
| SCHEMBL6800989 | 0.82 | SELP (0.45) | SELPTLR4LGALS8 | |
| SCHEMBL8431207 | 0.80 | SELP (0.43) | SELPTLR4LGALS8SYNJ2 | |
| SCHEMBL9332085 | 0.79 | SELP (0.31) | SELPTLR4 | |
| SCHEMBL9332104 | 0.77 | TLR4 (0.35) | TLR4 | |
| SCHEMBL8432784 | 0.75 | SSTR5 (0.43) | SELPTLR4 | |
| SCHEMBL8434745 | 0.75 | LGALS8 (0.43) | SELPTLR4LGALS8SYNJ2 | |
| SCHEMBL8436248 | 0.75 | SELP (0.39) | SELPTLR4LGALS8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352811-A | To produce homoallylic alcohol, acylation, oxidation of double bond | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-10-04 | — | — | US | disclosed |
| US-5158941-A | Lipid A analog as stimulant for production of interleukin-1 in human monocytes and tumor cell growth inhibitor | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-10-27 | — | — | US | disclosed |