Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 7/20 | 0.65 |
| ▸ | FNTB | P49356 | 7/20 | 0.65 |
| ▸ | SLC6A15 | Q9H2J7 | 13/20 | 0.58 |
| ▸ | HRH1 | P35367 | 5/20 | 0.58 |
| ▸ | PTAFR | P25105 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.57 |
| ▸ | GMNN | O75496 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9333282 | 0.93 | PTAFR (0.59) | FNTAFNTBSLC6A15HRH1PTAFR | |
| SCHEMBL9380680 | 0.91 | PTAFR (0.55) | FNTAFNTBSLC6A15HRH1PTAFR | |
| SCHEMBL9333210 | 0.90 | FNTA (0.52) | FNTAFNTBSLC6A15HRH1PTAFR | |
| SCHEMBL9332766 | 0.90 | FNTA (0.52) | FNTAFNTBSLC6A15HRH1PTAFR | |
| SCHEMBL9332755 | 0.89 | FNTA (0.63) | FNTAFNTBSLC6A15HRH1PTAFR | |
| SCHEMBL9332709 | 0.89 | FNTA (0.63) | FNTAFNTBSLC6A15HRH1PTAFR | |
| SCHEMBL9705980 | 0.88 | FNTA (0.48) | FNTAFNTBSLC6A15HRH1PTAFR | |
| SCHEMBL9336118 | 0.87 | FNTA (0.62) | FNTAFNTBSLC6A15HRH1PTAFR | |
| SCHEMBL9384242 | 0.87 | SLC6A15 (0.57) | FNTAFNTBSLC6A15HRH1PTAFR | |
| SCHEMBL9333178 | 0.83 | FNTA (0.46) | FNTAFNTBHRH1PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5358953-A | For treatment of allergic rhinitis | PFIZER INC. (US) | 1994-10-25 | — | — | US | claimed |
| EP-0572425-B1 | IMIDAZOPYRIDINE PAF/H 1 ANTAGONISTS | PFIZER LTD (GB) | 1994-08-03 | — | — | EP | claimed |
| WO-1992014734-A1 | IMIDAZOPYRIDINE PAF/H1 ANTAGONISTS | PFIZER LIMITED (GB) | 1992-09-03 | — | — | WO | claimed |
| US-5358953-A | For treatment of allergic rhinitis | PFIZER INC. (US) | 1994-10-25 | — | — | US | disclosed |
| EP-0572425-B1 | IMIDAZOPYRIDINE PAF/H 1 ANTAGONISTS | PFIZER LTD (GB) | 1994-08-03 | — | — | EP | disclosed |
| WO-1992014734-A1 | IMIDAZOPYRIDINE PAF/H1 ANTAGONISTS | PFIZER LIMITED (GB) | 1992-09-03 | — | — | WO | disclosed |